682341-17-9

Basic information

• Product Name: 2-Azetidinone,1-(2-aminophenyl)-(9CI)
• Synonyms: 2-Azetidinone,1-(2-aminophenyl)-(9CI)
• CAS NO: 682341-17-9
• Molecular Formula: C₉H₁₀N₂O
• Molecular Weight: 162.1885
• Product Categories: AMINETERTIARY
• Mol File: 682341-17-9.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-Azetidinone,1-(2-aminophenyl)-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Azetidinone,1-(2-aminophenyl)-(9CI)(682341-17-9)
• EPA Substance Registry System: 2-Azetidinone,1-(2-aminophenyl)-(9CI)(682341-17-9)

Safety Data

• Hazardous Substances Data: 682341-17-9(Hazardous Substances Data)

Upstream product

• 930-21-2 2-azetidinone 
• 615-36-1 2-bromoaniline 
• 615-43-0 2-iodophenylamine 

Relevant articles and documents

Synthesis of Medium Ring Nitrogen Heterocycles via a Tandem Copper-Catalyzed C-N Bond Formation-Ring-Expansion Process

A simple method for the preparation of medium ring heterocycles (7-, 8-, 9-, and 10-membered) has been developed. The process employs a Cu-catalyzed coupling of a β-lactam with an aryl bromide or iodide followed by intramolecular attack of a pendant amino group. In some instances, the intermediate β-lactam is observable but can be converted to the aza-heterocycle by catalysis. Acetic acid was found to be superior to transition metal complexes as a catalyst for this ring-expansion process.