6828-41-7Relevant articles and documents
Homoserine lactone derivatives, preparation method thereof and pharmaceutical composition for prevention or treatment of the periodontal diseases containing the same as an active ingredient
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Paragraph 0124-0126, (2017/04/14)
The present invention relates to homoserine lactone derivatives, optical isomers of the same, or pharmaceutically acceptable salts of the same. The homoserine lactone derivatives in the present invention have excellent properties as a quorum sensing antagonist which hinders communications among bacteria. According to the present invention, the homoserine lactone derivatives can hinder gene expressions of bacteria while effectively blocking formation of biofilm which is known to raise resistance against antibiotics, and suppress propagation of bacteria, thereby being useful as a pharmaceutical composition for preventing or treating periodontal diseases.
Genetic Engineering of Streptomyces coelicolor A3(2) for the enantioselective reduction of unnatural β-keto-ester substrates
Anson, Christopher E.,Bibb, Maureen J.,Booker-Milburn, Kevin I.,Clissold, Cole,Haley, Patrick J.,Hopwood, David A.,Ichinose, Koji,Revill, W. Peter,Stephenson, G. Richard,Surti, Chandres M.
, p. X224-227 (2007/10/03)
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