69180-50-3

Basic information

• Product Name: BIS(ACETATO-O)(3-METHOXYPHENYL)IODINE
• Synonyms: AURORA KA-4155;BIS(ACETATO-O)(3-METHOXYPHENYL)IODINE;Bis(acetato-O)(3-methoxyphenyl)iodine,98%
• CAS NO: 69180-50-3
• Molecular Formula: C₁₁H₁₃IO₅
• Molecular Weight: 352.12
• Mol File: 69180-50-3.mol
• Article Data: 16

Chemical Properties

• Melting Point: 134-138 °C
• Appearance: /
• Density: 1.6531 (estimate)
• CAS DataBase Reference: BIS(ACETATO-O)(3-METHOXYPHENYL)IODINE(CAS DataBase Reference)
• NIST Chemistry Reference: BIS(ACETATO-O)(3-METHOXYPHENYL)IODINE(69180-50-3)
• EPA Substance Registry System: BIS(ACETATO-O)(3-METHOXYPHENYL)IODINE(69180-50-3)

Safety Data

• Safety Statements: 24/25
• Hazardous Substances Data: 69180-50-3(Hazardous Substances Data)

Usage

Chemical Properties

OFF-WHITE TO LIGHT CREAM CRYSTALS OR POWDER

InChI:InChI=1/C11H13IO5/c1-8(13)16-12(17-9(2)14)10-5-4-6-11(7-10)15-3/h4-7H,1-3H3

Upstream product

• 766-85-8 3-methoxy-1-iodobenzene 
• 108-24-7 acetic anhydride 
• 64-19-7 acetic acid 
• 127-09-3 sodium acetate 
• 100-66-3 methoxybenzene 
• 79-21-0 peracetic acid 

Downstream Products

• 125879-18-7 1-Ethyl-7-methoxy-3-(3-methoxyphenyliodonio)-2-oxo-1,2-dihydro-4-chinolinolat 
• 33877-04-2 ethyl (E)-3-(3-methoxyphenyl)acrylate 
• 181517-73-7 tert-butyl (E)-3-(3-methoxyphenyl)propenoate 
• 346586-17-2 (E)-n-butyl 3-(3-methoxyphenyl)acrylate 

Relevant articles and documents

Preparation and Synthetic Applicability of Imidazole-Containing Cyclic Iodonium Salts

A novel approach to the preparation of imidazole-substituted cyclic iodonium salts has been developed via the oxidative cyclization of 1-phenyl-5-iodoimidazole using a cheap and available Oxone/H2SO4 oxidative system. The structure of the new polycyclic heteroarenes has been confirmed by single-crystal X-ray diffractometry, revealing the characteristic structure features for cyclic iodonium salts. The newly produced imidazole-flanked cyclic iodonium compounds were found to readily engage in a heterocyclization reaction with elemental sulfur, affording benzo[5,1-b]imidazothiazoles in good yields.

Iodine(III) Reagent-Mediated Intramolecular Amination of 2-Alkenylanilines to Prepare Indoles

A variety of 3-substituted and 2,3-disubstituted indoles were synthesized efficiently in good yields through the intramolecular amination of 2-alkenylanilines promoted by readily available iodine(III) reagents in a short reaction time. Mechanistic studies showed that the reaction pathway went through a nitrenium ion and that 3-acetoxy indoline was the key intermediate in the indole formation. The indole product was easily prepared on a gram scale and amination also proceeded smoothly using catalytic 3,5-dimethylphenyl iodine in the presence of mCPBA. Furthermore, the indolo[3,2-a]carbazole scaffold was prepared in good yield in six steps from commercial ortho-iodoaniline. (Figure presented.).

An Investigation of (Diacetoxyiodo)arenes as Precursors for Preparing No-Carrier-Added [18F]Fluoroarenes from Cyclotron-Produced [18F]Fluoride Ion

Treatment of (diacetoxyiodo)arenes (1a-1u) with cyclotron-produced [18F]fluoride ion rapidly affords no-carrier-added [18F]fluoroarenes (2a-2u) in useful yields and constitutes a new method for converting substituted iodoarenes into substituted [18F]fluoroarenes in just two steps.