69491-47-0

Basic information

• Product Name: 5-(4-METHOXYPHENYL)PYRIMIDINE
• Synonyms: 5-(4-METHOXYPHENYL)PYRIMIDINE;AKOS BAR-0657
• CAS NO: 69491-47-0
• Molecular Formula: C₁₁H₁₀N₂O
• Molecular Weight: 186.21
• Mol File: 69491-47-0.mol
• Article Data: 31

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 5-(4-METHOXYPHENYL)PYRIMIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(4-METHOXYPHENYL)PYRIMIDINE(69491-47-0)
• EPA Substance Registry System: 5-(4-METHOXYPHENYL)PYRIMIDINE(69491-47-0)

Safety Data

• Hazardous Substances Data: 69491-47-0(Hazardous Substances Data)

Upstream product

• 24903-95-5 nopinone 
• 7089-25-0 2-(4-methoxyphenyl)-3-(dimethylamino)allylidene(dimethyl)ammonium perchlorate 
• 3473-63-0 formamidine acetic acid 
• 82525-13-1 (Z)-2-(4-Methoxy-phenyl)-3-methylsulfanyl-propenal 
• 7089-34-1 ((E)-3-Dimethylamino-2-phenyl-allylidene)-dimethyl-ammonium; perchlorate 
• 4595-59-9 5-bromopyrimidine 
• 5720-07-0 4-methoxyphenylboronic acid 
• 17180-94-8 5-chloropyrimidine 
• 14846-66-3 trans-1-methoxy-4-(2-methylsulfanylvinyl)benzene 
• 123-11-5 4-methoxy-benzaldehyde 
• 97302-05-1 di-4-methoxyphenylzinc 
• 2036-41-1 5-methylpyrimidine 
• 70744-47-7 (p-methoxyphenyl)tri-n-butylstannane 
• 104-92-7 1-bromo-4-methoxy-benzene 

Downstream Products

• 74963-12-5 5-(p-anisyl)-N-phenacylpyrimidinium bromide 
• 69491-51-6 5-(p-hydroxyphenyl)pyrimidine 
• 925436-68-6 5-(4-{3-[4-(1-trityl-1H-imidazol-4-ylmethyl)-piperidin-1-yl]-propoxy}-phenyl)-pyrimidine 
• 893734-29-7 4-(pyrimidin-5-yl)benzonitrile 

Relevant articles and documents

Selective Synthesis of Substituted Pyridines and Pyrimidines through Cascade Annulation of Isopropene Derivatives

Diverse substituted pyridines and pyrimidines with high selectivity were obtained using a concise and efficient protocol developed herein. The reaction proceeds via metal-free cascade annulation of isopropene derivatives. Using isopropene derivatives as C3 synthons, NH4I as the “N” source, and formaldehyde or dimethyl sulfoxide as the carbon source, this reaction realizes the efficient formation of intermolecular C-N and C-C bonds.

Synthesis of Enaminone-Pd(II) Complexes and Their Application in Catalysing Aqueous Suzuki-Miyaura Cross Coupling Reaction

A series of Pd(II)-enaminone complexes, termed Pd(eao)2, have been synthesized and characterized. The investigation on the catalytic activities of these new Pd(II)-reagents has proved that the Pd(eao)2-1 possesses excellent catalytic activity for the Suzuki- Miyaura cross coupling reactions of aryl bromides/chlorides with aryl/vinyl boronic acids in the environmentally benign media of aqueous PEG400 at low loading (5 mol‰). The superiority of this Pd(II)-reagent to those commercial Pd(II) and Pd(0) catalysts in catalyzing the reactions has been confirmed by parallel experiments. What's more, Pd(eao)2-2 has been found as a practical catalyst for the homo-coupling reactions of aryl boronic acids.

Denitrogenative palladium-catalyzed coupling of aryl halides with arylhydrazines under mild conditions

The development of a method for the Pd(ii)-catalyzed denitrogenative coupling of arylhydrazines to give functionalized biaryls in good yield, using aryl bromides or aryl iodides as convenient and inexpensive aryl sources, is reported. High functional group tolerance is demonstrated for electronically distinct arylhydrazines as well as aryl halides. The desired products were isolated in good to excellent yields for 58 examples. Control experiments and mechanism studies revealed that the transformation undergoes a base-promoted Pd-catalyzed process.