6963-62-8

Basic information

• Product Name: 1H-Pyrazole-3-carboxylic acid, 4-phenyl-, ethyl ester
• Synonyms: 1H-Pyrazole-3-carboxylic acid, 4-phenyl-, ethyl ester;Ethyl 4-phenyl-1H-pyrazole-3-carboxylate;NSC 55495
• CAS NO: 6963-62-8
• Molecular Formula: C₁₂H₁₂N₂O₂
• Molecular Weight: 216.23588
• Mol File: 6963-62-8.mol
• Article Data: 6

Chemical Properties

• Melting Point: 164-165℃
• Boiling Point: 428.5°Cat760mmHg
• Flash Point: 212.9°C
• Appearance: /
• Density: 1.196g/cm³
• Vapor Pressure: 1.51E-07mmHg at 25°C
• Refractive Index: 1.575
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 1H-Pyrazole-3-carboxylic acid, 4-phenyl-, ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Pyrazole-3-carboxylic acid, 4-phenyl-, ethyl ester(6963-62-8)
• EPA Substance Registry System: 1H-Pyrazole-3-carboxylic acid, 4-phenyl-, ethyl ester(6963-62-8)

Safety Data

• Hazardous Substances Data: 6963-62-8(Hazardous Substances Data)

Usage

General Description

1H-Pyrazole-3-carboxylic acid, 4-phenyl-, ethyl ester is a chemical compound that belongs to the family of Pyrazoles. Pyrazoles are organic compounds characterized by a five-membered aromatic ring containing three carbon atoms and two nitrogen atoms. The ethyl ester functionality indicates the presence of an ester functional group on the ethyl (having two carbon atom) chain. The 4-phenyl indicates the presence of a phenyl group (a functional group made up of six carbon atoms, essentially a benzene ring minus a hydrogen atom) attached to the pyrazole ring. This chemical is often used in laboratory settings, but its specific properties and applications can vary widely depending on additional functional groups, substituents, or structural modifications.

InChI:InChI=1/C12H12N2O2/c1-2-16-12(15)11-10(8-13-14-11)9-6-4-3-5-7-9/h3-8H,2H2,1H3,(H,13,14)

Upstream product

• 623-73-4 diazoacetic acid ethyl ester 
• 98-86-2 acetophenone 
• 5292-53-5 diethyl benzalmalonate 
• 2725-60-2 1-(p-methylphenylsulfonyl)-1-diazopropan-2-one 
• 620-80-4 ethyl 2-benzylidene acetoacetate 
• 27262-63-1 ethyl 2-diazo-3-hydroxy-3-phenylbutanoate 
• 14802-30-3 (E)-1-(4-methylphenyl)-3-phenyl-2-propen-1-one 
• 72758-71-5 3c-phenyl-1-p-tolyl-propenone 
• 187158-58-3 5-(4-Methyl-benzoyl)-4-phenyl-3,4-dihydro-2H-pyrazole-3-carboxylic acid ethyl ester 
• 126580-13-0 ethyl 2-diazo-3-phenyl-3-butenoate 
• 102-96-5 (2-nitroethenyl)benzene 

Downstream Products

• 10199-68-5 4-phenyl-1H-pyrazole 
• 142598-52-5 ethyl 1-methyl-4-phenyl-1H-pyrazole-5-carboxylate 
• 7510-56-7 4-phenyl-1H-pyrazole-3-carboxylic acid 
• 94033-65-5 4-phenyl-1⁽²⁾H-pyrazole-3-carboxylic acid hydrazide 
• 142598-53-6 2-methyl-4-phenyl-2H-pyrazole-3-carboxylic acid 

Relevant articles and documents

1,3-Dipolar cycloaddition of chalcones and arylidene-1,3-dicarbonyls with diazosulfone for the regioselective synthesis of functionalized pyrazoles and pyrazolines

A convenient method for the synthesis of 3-acylpyrazoles and pyrazole-3-carboxylates using diazosulfone as a reactive 1,3-dipole and a diazomethane equivalent is reported here. Chalcones, arylidenemalonates and other arylidene-1,3-dicarbonyls performed we

Efficient method for the synthesis of functionalized pyrazoles by catalyst-free one-pot tandem reaction of nitroalkenes with ethyl diazoacetate

The one-pot synthesis of multisubstituted pyrazole derivatives was achieved via catalyst-free 1,3-dipolar cycloaddition of ethyl diazoacetate and nitroalkenes as the key step and elimination of the leaving group (NO 2 or Br) followed by intramo

Synthesis and reactions of some ethyl 3(5)aroyl-4-aryl-2-pyrazoline-5(3)carboxylates

A series of ethyl 3(5)aroyl-4-aiyl-2-pyrazoline-5(3)carboxylates 1 was prepared. Their reactions with bromine water, potassium permanganate and potassium hydroxide afforded the corresponding pyrazoles. With aryl and aroyl hydrazines the pyrazolines 1 gave the Schiff bases 9 while with hydrazine hydrate they yielded the corresponding acid hydrazides 11. Condensation of 11 with aromatic aldehydes gave the arylidene derivatives 12, which, on cyclization with the propar reagent, afforded 13 or 14. Reaction of 1 with hydrochloric acid gave the corresponding dipyrazolo-pyrazine derivatives 10.