69668-93-5Relevant articles and documents
Relative rates of hydrosilylation of representative alkenes and alkynes by Cp*2YMe·THF and [Cp2sYMe]2
Molander, Gary A.,Knight, Elizabeth E.
, p. 7009 - 7012 (1998)
Reactivity in the hydrosilylation of alkenes and alkynes catalyzed by the organoyttrium catalysts Cp*2YMe·THF and [Cp2SYMe]2 is generally determined by the steric environment of the substrate. Alkynes and conjugated alkenes show an increased reaction rate because of electronic effects; the magnitude of this increase is highly substrate dependent. The electron rich pyrrole system is particularly reactive, especially with the sterically open [Cp2TMSYMe]2 precatalyst. For nonconjugated substrates, Cp*2YMe·THF is generally a more selective catalyst than [Cp2TMSYMe]2.
Nickel-Catalyzed Asymmetric Friedel-Crafts Propargylation of 3-Substituted Indoles with Propargylic Carbonates Bearing an Internal Alkyne Group
Miyazaki, Yusuke,Zhou, Biao,Tsuji, Hiroaki,Kawatsura, Motoi
supporting information, p. 2049 - 2053 (2020/03/04)
The nickel-catalyzed highly enantioselective Friedel-Crafts propargylation of 3-substituted indoles with propargylic carbonates bearing an internal alkyne group was developed. A wide array of the propargylic carbonates as well as 3-substituted indoles can be applicable to the asymmetric nickel catalysis, providing the corresponding chiral C-3 propargylated indolenine derivatives bearing two vicinal chiral centers in up to 89% yield with up to >99% ee and 94:6 dr (24 examples).
Ruthenium-catalyzed [2 + 2] cycloadditions between norbornene and propargylic alcohols or their derivatives
Tsui, Gavin C.,Villeneuve, Karine,Carlson, Emily,Tam, William
, p. 3847 - 3856 (2014/08/18)
Diastereoselective ruthenium-catalyzed [2 + 2] cycloadditions of norbornene and propargylic alcohols or their derivatives were investigated. The cycloadditions were found to be highly stereoselective, giving exo cycloadducts in moderate to excellent yields with diastereoselectivities up to 92:8. When a chiral propargylic alcohol was used in the cycloaddition, up to 80% ee of the [2 + 2] cycloadducts was observed after oxidation of the alcohol.
