6974-72-7 Usage
Description
Pyridine-2-carboxamide 1-oxide, also known as nicotinamide N-oxide, is a chemical compound with the formula C6H5NO2. It is a derivative of pyridine and has a nitroso functional group attached to the carboxamide group. Nicotinamide N-oxide is a pale yellow to light brown solid at room temperature and is soluble in water.
Uses
Used in Organic Synthesis:
Pyridine-2-carboxamide 1-oxide is used as a reagent in organic synthesis for its versatile chemical properties and ability to form various intermediates.
Used in Pharmaceutical Industry:
Pyridine-2-carboxamide 1-oxide is used as a precursor to various pharmaceutical compounds due to its unique structure and reactivity.
Used in Neuroprotection:
Pyridine-2-carboxamide 1-oxide is being studied for its potential use in the treatment of various neurodegenerative and inflammatory conditions, as it has been found to have protective effects on cells.
Used in Dye and Pigment Production:
Pyridine-2-carboxamide 1-oxide is used in the production of dyes, pigments, and other chemicals, leveraging its chemical properties for color development and stability.
Check Digit Verification of cas no
The CAS Registry Mumber 6974-72-7 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,9,7 and 4 respectively; the second part has 2 digits, 7 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 6974-72:
(6*6)+(5*9)+(4*7)+(3*4)+(2*7)+(1*2)=137
137 % 10 = 7
So 6974-72-7 is a valid CAS Registry Number.
InChI:InChI=1/C6H6N2O2/c7-6(9)5-3-1-2-4-8(5)10/h1-4H,(H2,7,9)
6974-72-7Relevant articles and documents
Oxidation of tertiary nitrogen compounds to N-oxides by molecular oxygen-aldehyde system in the absence of metal catalyst
Dongre,Venkateshwar Rao,Sharma,Sain,Bhatia
, p. 167 - 172 (2007/10/03)
A variety of tertiary nitrogen compounds have been oxidized to corresponding N-oxides in near quantitative yields by molecular oxygen/2-methylpropanal system in the absence of metal catalyst.
ELUCIDATION OF THE REACTION PATH FOR THE NITROSATION OF 2- AND 4-METHYLPYRIDINE 1-OXIDES WITH ALKYL NITRITE IN LIQUID AMMONIA
Tagawa, Yoshinobu,Togashi, Hideo,Goto, Yoshinobu
, p. 327 - 336 (2007/10/02)
The reaction path for the nitrosation of 2- and 4-methylpyridine 1-oxides with alkyl nitrite in the presence of NaNH2 in liquid NH3 was elucidated experimentally, and theoretically by the use of a semiempirical molecular orbital method (PM3 method).In the case of the nitrosation of 4-methylpyridine 1-oxide at room temperature, only 4-pyridinecarboxamide 1-oxide was obtained, while at -33 deg C a thermodynamically unstable aldoxime, (Z)-4-pyridinecarbaldehyde 1-oxide oxime, which was easily transformed into E-form by heating, was obtained.On the other hand, the nitrosation of 2-methylpyridine 1-oxide gave only a thermodynamically stable aldoxime, (E)-2-pyridinecarbaldehyde 1-oxide oxime, both at room temperature and at -33 deg C.These results were reasonably explained by PM3 method.