69901-75-3 Usage
Description
Cbz-Cyclohexyl-L-glycine, a glycine derivative, is a white to off-white solid with significant applications in the pharmaceutical industry. It is characterized by its ability to be used in the preparation of peptides, which serve as inhibitors of serine proteases, particularly the hepatitis C virus NS3-NS4A protease.
Uses
Used in Pharmaceutical Industry:
Cbz-Cyclohexyl-L-glycine is used as a building block for the synthesis of peptides that act as inhibitors of serine proteases. Its primary application is in the development of treatments targeting the hepatitis C virus NS3-NS4A protease, which plays a crucial role in the viral replication process.
The use of Cbz-Cyclohexyl-L-glycine in the pharmaceutical industry is driven by its potential to contribute to the creation of effective antiviral therapies against hepatitis C, a viral disease that affects millions of people worldwide. By inhibiting the NS3-NS4A protease, these peptides can disrupt the virus's life cycle and help in the development of novel treatment strategies.
Check Digit Verification of cas no
The CAS Registry Mumber 69901-75-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,9,9,0 and 1 respectively; the second part has 2 digits, 7 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 69901-75:
(7*6)+(6*9)+(5*9)+(4*0)+(3*1)+(2*7)+(1*5)=163
163 % 10 = 3
So 69901-75-3 is a valid CAS Registry Number.
InChI:InChI=1/C16H21NO4/c18-15(19)14(13-9-5-2-6-10-13)17-16(20)21-11-12-7-3-1-4-8-12/h1,3-4,7-8,13-14H,2,5-6,9-11H2,(H,17,20)(H,18,19)/t14-/m0/s1
69901-75-3Relevant articles and documents
PROCESS FOR PRODUCING N-PROTECTED AMINO ACID
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Page/Page column 3, (2011/07/06)
The present invention relates to a method for producing N-protected amino acid. Specifically, the present invention provides a method in which a protecting group is introduced to the amino group of an amino acid in a reaction under alkaline condition, and the N-protected amino acid thus generated is then separated from the reaction solution as crystals, without undergoing an extraction step or a concentration step. The present inventors have completed the invention based on the finding that desirable crystals of N-protected amino acids may be obtained without extraction, concentration or recrystallization steps between the initial generation of the N-protected amino acid molecules and the subsequent separation of the crystals, by first adding an water-soluble organic solvent and optionally water to the reaction solution (alkaline) containing the N-protected amino acid, and then neutralizing the solution by an acid.