702-96-5 Usage
Description
2,2,5,5-Tetramethyl-3-pyrrolidinecarboxamide, also known as 2,2,5,5-Tetramethylpyrrolidine-3-carboxamide, is a carboxamide of a hydrogenated pyrrole derivative. It is an off-white solid and has been synthesized through the hydrogenation of 2,2,5,5-tetramethyl-3-pyrroline-3-carboxamide. 2,2,5,5-TETRAMETHYL-3-PYRROLIDINECARBOXAMIDE has demonstrated antiarrhythmic activity in some of its derivatives, making it a promising candidate for further research and development in the pharmaceutical industry.
Uses
Used in Organic Synthesis:
2,2,5,5-Tetramethyl-3-pyrrolidinecarboxamide is used as an intermediate in organic synthesis for the development of various chemical compounds. Its unique structure and properties allow it to be a valuable building block in the creation of new molecules with potential applications in various industries.
Used in the Synthesis of Nitroxide Radicals:
2,2,5,5-Tetramethyl-3-pyrrolidinecarboxamide is used as a precursor in the synthesis of its nitroxide, 3-carbamoyl-2,2,5,5-tetramethyl-1-pyrrolidinyloxy free radical. These nitroxide radicals have potential applications in the field of materials science, particularly in the development of stable free radicals for use in polymerization processes and other chemical reactions.
Used in Pharmaceutical Research:
The antiarrhythmic activity of some derivatives of 2,2,5,5-tetramethylpyrrolidine-3-carboxamide has been evaluated, indicating its potential use in the development of new drugs for the treatment of cardiac arrhythmias. Further research and development in this area could lead to the creation of novel therapeutic agents for various cardiovascular conditions.
Used in Chemical Research:
As a hydrogenated pyrrole derivative, 2,2,5,5-tetramethyl-3-pyrrolidinecarboxamide may be used in chemical research to study the properties and reactions of similar compounds. This can contribute to the advancement of knowledge in the field of organic chemistry and potentially lead to the discovery of new applications and uses for related compounds.
Check Digit Verification of cas no
The CAS Registry Mumber 702-96-5 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 7,0 and 2 respectively; the second part has 2 digits, 9 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 702-96:
(5*7)+(4*0)+(3*2)+(2*9)+(1*6)=65
65 % 10 = 5
So 702-96-5 is a valid CAS Registry Number.
InChI:InChI=1/C9H18N2O/c1-8(2)5-6(7(10)12)9(3,4)11-8/h6,11H,5H2,1-4H3,(H2,10,12)/p+1/t6-/m1/s1
702-96-5Relevant articles and documents
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Chion et al.
, p. 2682,2683, 2687 (1978)
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The effect of the nature of the substituent at the nitrogen atom on transformations of 3-bromo-2,2,6,6-tetramethyl-4-piperidinone and its 1-hydroxy and 1-oxyl derivatives under conditions of the Favorsky rearrangement
Krinitskaya
, p. 1140 - 1142 (2007/10/03)
3-Bromo-2,2,6,6-tetramethyl-4-oxopiperidine-1-oxyl reacts with NH4OH to give 3-carbamoyl-2,2,5,5-tetramethylpyrrolidine-1-oxyl, a product of the Favorsky rearrangement. 3-Bromo-2,2,6,6-tetramethyl-4-piperidinone is transformed under these conditions into a bicyclic amino ketone, while its 1-hydroxy derivative affords acyclic nitrosoenone.
INFLUENCE OF CHEMICAL STRUCTURE OF NITROXYL SPIN LABELS ON THEIR REDUCTION BY ASCORBIC ACID
Couet, W. R.,Brasch, R. C.,Sosnovsky, G.,Lukszo, J.,Prakash, I.,et. al.
, p. 1165 - 1172 (2007/10/02)
The influence of structure on the reduction of nitroxyl spin labels by ascorbic acid was examined using both piperidine and pyrrolidine nitroxyls.A five-fold molar excess of ascorbic acid and pH of 7.4 were used.The nitroxyl concentration was measured by electron spin resonance spectrometry.The five-membered (pyrrolidine) nitroxyls were more stable than the six-membered derivatives.Ring substituents also influenced the reaction.The anionic derivatives were more stable than the unionized compounds which, in turn, were more stable than the amines (cations at pH 7.4).
