70377-89-8 Usage
Explanation
The IUPAC name provides a standardized way to name chemical compounds. It includes the stereochemistry (2R,4R,5R), the functional groups (hydroxy, carboxaldehyde), and the core structure (1,3-dioxane).
Explanation
The compound is derived from 1,3-dioxane, which is a six-membered ring containing two oxygen atoms. It has a hydroxyl (-OH) group and a carboxaldehyde (-CHO) functional group attached to the ring.
Explanation
The stereochemistry indicates the orientation of the substituents on the carbon atoms. In this case, the hydroxyl group is attached to the 5th carbon (C5), the methyl group is attached to the 2nd carbon (C2), and the carboxaldehyde group is attached to the 4th carbon (C4). The (2R,4R,5R) notation specifies the clockwise arrangement of these substituents when viewed from the perspective of the hydrogen atom on the chiral carbon.
Explanation
The hydroxyl group is a polar covalent bond between oxygen and hydrogen, while the carboxaldehyde group is a combination of a carbonyl (C=O) and an aldehyde (-CHO) functional group. These functional groups contribute to the compound's reactivity and properties.
Explanation
Due to its unique structure and functional groups, 1,3-dioxane-4-carboxaldehyde, 5-hydroxy-2-methyl-, (2R,4R,5R)(9CI) is used as a building block in the synthesis of various biologically active molecules and pharmaceutical drug candidates.
Explanation
The presence of the hydroxyl and carboxaldehyde functional groups makes this compound a versatile building block for the synthesis of complex molecules. These functional groups can participate in various chemical reactions, such as oxidation, reduction, and condensation, allowing for the creation of a wide range of compounds.
Structure
1,3-Dioxane derivative with a hydroxyl group and a carboxaldehyde functional group
Stereochemistry
(2R,4R,5R)
Functional Groups
Hydroxyl (-OH) and Carboxaldehyde (-CHO)
Application
Organic synthesis and pharmaceutical research
Reactivity
Valuable building block for synthesis
Check Digit Verification of cas no
The CAS Registry Mumber 70377-89-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,0,3,7 and 7 respectively; the second part has 2 digits, 8 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 70377-89:
(7*7)+(6*0)+(5*3)+(4*7)+(3*7)+(2*8)+(1*9)=138
138 % 10 = 8
So 70377-89-8 is a valid CAS Registry Number.
70377-89-8Relevant articles and documents
NOVEL DIOL COMPOUNDS SYNTHESIS AND ITS USE FOR FORMAL SYNTHESIS OF (2R, 3 S)-3-HYDROXYPIPECOLIC ACID
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Page/Page column 7; 8, (2016/05/02)
The patent discloses novel diol derivatives of general formula I, [Formula should be inserted here] A chiral pool process for the synthesis of the compound of formula I from D glucose. Further, it discloses a process for the synthesis of (2R, 3S)-3-hydroxypipecolic acid from D- glucose using chiral pool approach, wherein the D-glucose used is in enantiomerically pure form.
Radical cyclization of oxime ethers derived from monosaccharides aiming at the synthesis of dysiherbaine and related stereoisomers
Naito, Takeaki,Nair,Nishiki, Akiyoshi,Yamashita, Kazuhiko,Kiguchi, Toshiko
, p. 2611 - 2615 (2007/10/03)
Stannyl radical-mediated cyclization of oxime ethers (6), (14), (22), and (29) derived from glucose and galactose afforded the cyclized aminosugar derivatives (7), (8), (15, 16 and 17), (23), (24), and (30, 31 and 32) which would serve as key intermediates for the synthesis of dysiherbaine and its isomers.
Synthesis and biological activity of 4-methyl-3,5-dioxane derivatives as thromboxane A2 receptor antagonists
Marusawa, Hiroshi,Setoi, Hiroyuki,Kuroda, Akio,Sawada, Akihiko,Seki, Jiro,Motoyama, Yukio,Tanaka, Hirokazu
, p. 2635 - 2645 (2007/10/03)
The synthesis and biological activity of novel 4-methyl-3,5-dioxane analogues are described. All compounds were produced through modification of the substituent formally corresponding to the ω-octenol side chain of thromboxane A2 (TXA2/su