70538-57-7 Usage
General Description
6-Nitroisoquinoline is an organic compound with the molecular formula C9H6N2O2. It is a nitro-substituted derivative of isoquinoline, and is used primarily as a building block in the synthesis of pharmaceuticals and dyes. Its chemical structure consists of a quinoline ring with a nitro group attached at the 6-position. 6-Nitroisoquinoline is a yellow solid with a melting point of 126-128°C and is sparingly soluble in water. It is considered to be a hazardous substance, and its handling and use should be done in a controlled environment with proper safety precautions.
Check Digit Verification of cas no
The CAS Registry Mumber 70538-57-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,0,5,3 and 8 respectively; the second part has 2 digits, 5 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 70538-57:
(7*7)+(6*0)+(5*5)+(4*3)+(3*8)+(2*5)+(1*7)=127
127 % 10 = 7
So 70538-57-7 is a valid CAS Registry Number.
70538-57-7Relevant articles and documents
Synthesis of Isoquinolines from Indenes
Miller, R. Bryan,Frincke, James M.
, p. 5312 - 5315 (2007/10/02)
A general procedure for the synthesis of isoquinolines from appropriately substituted indenes is described.Ozonolysis of the indenes followed by reductive workup gives intermediate homophthalaldehydes which are treated with ammonium hydroxide to give the isoquinolines.This "one-pot", three-step reaction sequence was applied to the formation of all of the mono-C-methyl-substituted isoquinolines in a regiospecific manner.The procedure is applicable to both electron-withdrawing and electron-donating substituents on the indene system.In this manner the 6- and 7-nitro-,-bromo-, and -iodoisoquinolines were prepared.