7054-25-3

Basic information

• Product Name: QUINIDINE GLUCONATE
• Synonyms: 6’-methoxy-cinchonan-9-o(9s)-cinchonan-9-omono-d-gluconate(salt);compd.withquinidine(1:1),d-gluconicaci;d-gluconicacid,compd.with(9s)-6’-methoxycinchonan-9-ol(1:1);quinidinemono-d-gluconate(salt);QUINIDINE GLUCONATE;QUINIDINE GLUCONATE SALT;QUINIDINEGLUCONATE,USP;Quinidine Gluconate (200 mg)
• CAS NO: 7054-25-3
• Molecular Formula: C₆H₁₂O₇*C₂₀H₂₄N₂O₂
• Molecular Weight: 520.57
• EINECS: 230-333-9
• Product Categories: Neat CompoundsAnalytical Standards;Alphabetic;Drugs&Metabolites;Forensic and Veterinary Standards;Q
• Mol File: 7054-25-3.mol
• Article Data: 0

Chemical Properties

• Melting Point: 175-176 C
• Appearance: /
• CAS DataBase Reference: QUINIDINE GLUCONATE(CAS DataBase Reference)
• NIST Chemistry Reference: QUINIDINE GLUCONATE(7054-25-3)
• EPA Substance Registry System: QUINIDINE GLUCONATE(7054-25-3)

Safety Data

• Hazard Codes: Xn,Xi
• Statements: 20/21/22-36/37/38
• Safety Statements: 36-26
• RIDADR: 1544
• WGK Germany: 3
• RTECS: LZ5250000
• HazardClass: 6.1(b)
• PackingGroup: III
• Hazardous Substances Data: 7054-25-3(Hazardous Substances Data)

Usage

Description

Quinidine Gluconate is a pharmaceutical compound that serves as a salt of Quinidine, a dextrorotatory stereoisomer of Quinine. It is recognized for its anti-arrhythmic properties and is classified as a class IA antiarrhythmic agent. In addition to its cardiac depressant effects, it also exhibits antimalarial activity.

Uses

Used in Pharmaceutical Industry:
Quinidine Gluconate is used as a cardiac depressant for its anti-arrhythmic properties, specifically in the treatment of various cardiac arrhythmias. It helps regulate the heart's rhythm and prevents abnormal heart contractions, thus maintaining a stable heartbeat.
Additionally, it is used as an antimalarial agent for the treatment of malaria, a disease caused by Plasmodium parasites. Its antimalarial activity aids in combating the infection and alleviating the symptoms associated with the disease.

Veterinary Drugs and Treatments

Quinidine is used in small animal or equine medicine for the treatment of ventricular arrhythmias (VPCs, ventricular tachycardia), refractory supraventricular tachycardias, and supraventricular arrhythmias associated with anomalous conduction in Wolff- Parkinson-White (WPW) syndrome. Chronic use of quinidine for controlling ventricular arrhythmias and supraventricular tachycardia in dogs has diminished over the years as other drugs appear to be more effective. It is still used in dogs and horses to convert atrial fibrillation to sinus rhythm. Oral therapy is generally not used in cats.

InChI:InChI=1/C20H24N2O2.C6H12O6/c1-3-13-12-22-9-7-14(13)10-19(22)20(23)16-6-8-21-18-5-4-15(24-2)11-17(16)18;7-1-3(9)5(11)6(12)4(10)2-8/h3-6,8,11,13-14,19-20,23H,1,7,9-10,12H2,2H3;1,3-6,8-12H,2H2/t13-,14-,19+,20-;3-,4+,5+,6+/m00/s1