70606-82-5Relevant articles and documents
Studies in the field of pyridazine compounds, III (1). Hypotensive 3-(1-pyrazolyl) pyridazine derivatives
Szilagyi,Kasztreiner,Tardos,et al.
, p. 439 - 445 (2007/10/05)
Substituted 3-(1-pyrazolyl)pyridazines were synthesized and their hypotensive activity was evaluated on anaesthetized normotensive cats and awake spontaneously hypertensive rats. Several relations were found between structure and hypotensive activity of the compounds. Some of the active compounds proved to be useful for detailed investigations. Most of the active compounds exerted an influence on prostaglandin metabolism.