70629-60-6Relevant articles and documents
Decarboxylative hydrazination of unactivated carboxylic acids by cerium photocatalysis
Yatham, Veera Reddy,Bellotti, Peter,K?nig, Burkhard
supporting information, p. 3489 - 3492 (2019/03/26)
We report the cerium photocatalyzed radical decarboxylative hydrazination of carboxylic acids with di-tert-butylazodicarboxylate (DBAD). The operationally simple protocol provides rapid access to synthetically useful hydrazine derivatives and overcomes current scope limitations in the photoredox-catalyzed decarboxylation of carboxylic acids.
1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-ones and 1,5-dihydro-4H-pyrazolo[4,3-c]pyridin-4-ones as PDE1 Inhibitors
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Paragraph 0197; 0198, (2017/10/30)
The present invention provides 1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-ones and 1,5-dihydro-4H-pyrazolo[4,3-c]pyridin-4-ones of formula (I) as PDE1 inhibitors and their use as a medicament, in particular for the treatment of neurodegenerative disorders and psychiatric disorders.
PROCESS FOR MAKING BENZOXAZEPIN COMPOUNDS
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Page/Page column 9; 24, (2014/09/29)
Processes are described for the preparation of PI3K inhibitor, GDC-0032, Formula (I), having the structure: Formula (I) (GDC-0032), and intermediates useful for the preparation of (I).