70637-05-7

Basic information

• Product Name: 2,6,7-Trioxabicyclo(2.2.2)octane, 4-t-butyl-1-phenyl-
• Synonyms: 2,6,7-Trioxabicyclo(2.2.2)octane, 4-t-butyl-1-phenyl-;4-t-butyl-1-phenyl-2,6,7-trioxabicyclo(2.2.2)octane;4-tert-butyl-1-phenyl-2,6,7-trioxabicyclo[2.2.2]octane;4-(1,1-Dimethylethyl)-1-phenyl-2,6,7-trioxabicyclo[2.2.2]octane;TBOB;t-Butylbicycloorthobenzoate
• CAS NO: 70637-05-7
• Molecular Formula: C15H20 O3
• Molecular Weight: 248.32
• Mol File: 70637-05-7.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 313.8°C at 760 mmHg
• Flash Point: 104.8°C
• Appearance: /
• Density: 1.149g/cm³
• Vapor Pressure: 0.000896mmHg at 25°C
• Refractive Index: 1.545
• CAS DataBase Reference: 2,6,7-Trioxabicyclo(2.2.2)octane, 4-t-butyl-1-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 2,6,7-Trioxabicyclo(2.2.2)octane, 4-t-butyl-1-phenyl-(70637-05-7)
• EPA Substance Registry System: 2,6,7-Trioxabicyclo(2.2.2)octane, 4-t-butyl-1-phenyl-(70637-05-7)

Safety Data

• Hazardous Substances Data: 70637-05-7(Hazardous Substances Data)

Usage

Description

2,6,7-Trioxabicyclo(2.2.2)octane, 4-t-butyl-1-phenyl-, also known as EBOB, is a synthetic compound that serves as a ligand in the study of GABAA receptors. It is used to investigate the binding properties and effects of central nervous system convulsants on these receptors, which play a crucial role in the regulation of neuronal excitability and are involved in various neurological disorders.

Uses

Used in Pharmaceutical Research:
2,6,7-Trioxabicyclo(2.2.2)octane, 4-t-butyl-1-phenylis used as a research ligand for studying the binding properties and effects of central nervous system convulsants on human α1β2γ2 and α2β2γ2 GABAA receptors. This application helps researchers understand the molecular mechanisms underlying the actions of convulsants and potentially develop new therapeutic strategies for neurological disorders.
Used in Neuroscience:
In the field of neuroscience, 2,6,7-Trioxabicyclo(2.2.2)octane, 4-t-butyl-1-phenylis used as a tool to investigate the role of GABAA receptors in the central nervous system. This knowledge can contribute to the development of novel treatments for conditions such as epilepsy, anxiety, and other neurological disorders that involve the dysregulation of neuronal excitability.
Used in Drug Development:
2,6,7-Trioxabicyclo(2.2.2)octane, 4-t-butyl-1-phenylis also used in the development of new drugs targeting GABAA receptors. By understanding the binding properties and effects of EBOB on these receptors, researchers can design more effective and selective drugs with fewer side effects, ultimately improving patient outcomes in the treatment of various neurological conditions.

InChI:InChI=1/C15H20O3/c1-13(2,3)14-9-16-15(17-10-14,18-11-14)12-7-5-4-6-8-12/h4-8H,9-11H2,1-3H3