708-66-7

Basic information

• Product Name: 4-(TRIFLUOROMETHYLSULFINYL)CHLOROBENZENE
• Synonyms: 4-(TRIFLUOROMETHYLSULPHINYL)CHLOROBENZENE;4-(TRIFLUOROMETHYLSULFINYL)CHLOROBENZENE;4-Chlorophenyl trifluoromethyl sulphoxide
• CAS NO: 708-66-7
• Molecular Formula: C₇H₄ClF₃OS
• Molecular Weight: 228.62
• Mol File: 708-66-7.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 80-81°C 12mm
• Flash Point: 102.3°C
• Appearance: /
• Density: 1.58g/cm³
• Vapor Pressure: 0.0449mmHg at 25°C
• Refractive Index: 1.542
• CAS DataBase Reference: 4-(TRIFLUOROMETHYLSULFINYL)CHLOROBENZENE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(TRIFLUOROMETHYLSULFINYL)CHLOROBENZENE(708-66-7)
• EPA Substance Registry System: 4-(TRIFLUOROMETHYLSULFINYL)CHLOROBENZENE(708-66-7)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36/37/39
• Hazardous Substances Data: 708-66-7(Hazardous Substances Data)

Usage

General Description

4-(Trifluoromethylsulfinyl)chlorobenzene is a chemical compound with the molecular formula C7H4ClF3OS. It is a colorless to pale yellow liquid with a pungent odor, and is primarily used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. It is also used in the manufacturing of various organic compounds, including insecticides and herbicides. The compound is classified as a chlorobenzene derivative, and its trifluoromethylsulfinyl group makes it a valuable building block in organic chemistry. Additionally, it is considered to be a potential environmental contaminant and is subject to regulatory restrictions in some jurisdictions due to its toxic and harmful effects on aquatic life and the environment.

InChI:InChI=1/C7H4ClF3OS/c8-5-1-3-6(4-2-5)13(12)7(9,10)11/h1-4H

Upstream product

• 2901-92-0 p-chlorophenylsulfinyl chloride 
• 81290-20-2 (trifluoromethyl)trimethylsilane 
• 1142-19-4 4,4'-dichlorodiphenyl disulfide 
• 108-90-7 chlorobenzene 
• 1948-15-8 <4-Chlor-2-nitro-phenyl>-trifluormethyl-sulfoxid 
• 1948-10-3 (2-Amino-4-chlor-phenyl)-trifluormethyl-sulfoxid 
• 407-16-9 4-chlorophenyl trifluoromethyl sulfide 

Downstream Products

• 1178899-25-6 N-acetyl-S-(p-chlorophenyl)-S-(trifluoromethyl)sulfilimine 
• 95414-69-0 S-((p-chloro)phenyl)-S-(trifluoromethyl)-sulfoximine 
• 95970-28-8 C₈H₄ClF₆NO₂S₂ 
• 1335015-55-8 N-(phenyl) (p-chloro)phenyl trifluoromethyl sulfoximine 
• 1260111-72-5 p-chlorophenyl trifluoromethyl sulfilimine 

Relevant articles and documents

Selective oxidation and chlorination of trifluoromethylsulfide using trichloroisocyanuric acid in ionic liquid

A route to chemoselective oxidation and chlorination of aryltrifluoromethylsulfide using trichloroisocyanuric acid (TCCA) in ionic liquid, an efficiently O-methylation reaction and a reduction of nitro- to amido- in excellent yields have been developed.

Nucleophilic trifluoromethylation of organic substrates using (trifluoromethyl)trimethylsilane in the presence of a fluoride anion. II. A convenient route to aryltrifluoromethyl-sulfides, - sulfoxides and -sulfones

Aryltrifluoromethyl-sulfides, -sulfoxides and -sulfones can be prepared by trifluoromethylation of the corresponding arylsulfenyl, -sulfinyl and -sulfonyl halides using (trifluoromethyl)trimethylsilane in the presence of fluoride sources, such as TASF . - Keywords: Nucleophilic trifluoromethylation; (Trifluoromethyl)trimethylsilane; Fluoride anion; Aryltrifluoromethylsulfides; Aryltrifluoromethylsulfoxides; Aryltrifluoromethylsulfones

FLUORO(TRIFLUOROMETHYL)ARYLSULFONIUM AND (TRIFLUOROMETHYL)DIARYLSULFONIUM SALTS

The oxygen atoms in aryl trifluoromethyl sulfoxides are substituted by fluorine during the action of the SF3(1+)*BF4(1-) and SF3(1+)*SbF6(1-) complexes.Fluoro(trifluoromethyl)arylsulfonium and (trifluoromethyl)diarylsulfonium salts were synthesized.The la