709-96-6 Usage
Description
2-Methyl-4-(trifluoromethylthio)phenol, with the molecular formula C8H7F3OS, is a phenolic compound characterized by the presence of a trifluoromethylthio group attached to its aromatic ring. This chemical intermediate is known for its reactivity and should be handled with care due to potential health and environmental concerns.
Uses
Used in Pharmaceutical Industry:
2-Methyl-4-(trifluoromethylthio)phenol is used as a chemical intermediate for the synthesis of various pharmaceutical chemicals. Its unique structure contributes to the development of new drugs with specific therapeutic properties.
Used in Agricultural Industry:
In the agricultural sector, 2-Methyl-4-(trifluoromethylthio)phenol serves as an intermediate in the production of agrochemicals, aiding in the development of effective pesticides and other crop protection agents.
Used as an Antioxidant:
2-Methyl-4-(trifluoromethylthio)phenol is utilized as an antioxidant in various industrial applications, helping to prevent the oxidation of materials and extend their shelf life.
Used as a Preservative:
2-METHYL-4-(TRIFLUOROMETHYLTHIO)PHENOL also functions as a preservative, protecting products from spoilage and degradation, thus maintaining their quality and safety for use.
Check Digit Verification of cas no
The CAS Registry Mumber 709-96-6 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 7,0 and 9 respectively; the second part has 2 digits, 9 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 709-96:
(5*7)+(4*0)+(3*9)+(2*9)+(1*6)=86
86 % 10 = 6
So 709-96-6 is a valid CAS Registry Number.
InChI:InChI=1/C8H7F3OS/c1-5-4-6(2-3-7(5)12)13-8(9,10)11/h2-4,12H,1H3
709-96-6Relevant articles and documents
Acid-promoted direct electrophilic trifluoromethylthiolation of phenols
Jereb, Marjan,Gosak, Kaja
, p. 3103 - 3115 (2015/04/27)
The electrophilic aromatic ring trifluoromethylthiolation of various substituted phenols was accomplished using PhNHSCF3 (N-trifluoromethylsulfanyl)aniline, (1) in the presence of BF3·Et2O (2) or triflic acid as the promoter. The functionalization was exclusively para-selective; phenols unsubstituted in both the ortho- and para positions solely gave the para-substituted SCF3-products in all cases, while para-substituted phenols gave the ortho-substituted SCF3-products. 3,4-Dialkyl substituted phenols yielded the corresponding products according to the Mills-Nixon effect, and estrone and estradiol furnished biologically interesting SCF3-analogues. The highly reactive catechol and pyrogallol substrates gave the expected products smoothly in the presence of BF3·Et2O, whereas less reactive phenols required triflic acid. 2-Allylphenol gave the expected p-SCF3 analogue, which underwent an addition/cyclization sequence and furnished a new di-trifluoromethylthio substituted 2,3-dihydrobenzofuran derivative. Some additional transformations of 4-(trifluoromethylthio)phenol with NBS, NIS, HNO3, HNO3/H2SO4 and 4-bromobenzyl bromide were performed giving bromo-, iodo-, nitro- and benzyl substituted products. The latter derivative underwent Suzuki-Miyaura coupling with phenylboronic acid.
