71254-91-6 Usage
Description
1-(P-Tosyl)-3,4,4-trimethyl-2-imidazolinium iodide, with the molecular formula C15H24IN2O2S, is a quaternary salt that serves as a highly selective and efficient catalyst in various organic synthesis reactions. It is particularly known for its ability to facilitate the formation of carbon-heteroatom bonds, which is crucial in the synthesis of biologically active molecules and pharmaceuticals. The presence of the tosyl group in its structure ensures stability and compatibility with a variety of reaction conditions, making this compound a versatile and valuable tool in the field of organic chemistry.
Uses
Used in Organic Synthesis:
1-(P-Tosyl)-3,4,4-trimethyl-2-imidazolinium iodide is used as a catalyst for facilitating the formation of carbon-heteroatom bonds in organic synthesis. Its application is particularly valuable in the synthesis of biologically active molecules and pharmaceuticals, where the formation of such bonds is crucial.
Used in Cross-Coupling Reactions:
In the field of organic chemistry, 1-(P-Tosyl)-3,4,4-trimethyl-2-imidazolinium iodide is also used as a reagent in the formation of carbon-carbon bonds through cross-coupling reactions. This capability further expands its utility in creating complex molecular structures that are important in the development of new pharmaceuticals and other organic compounds.
Used in Pharmaceutical Industry:
1-(P-Tosyl)-3,4,4-trimethyl-2-imidazolinium iodide is used as a catalyst in the pharmaceutical industry for the synthesis of biologically active molecules. Its ability to promote the formation of carbon-heteroatom bonds makes it a valuable tool in the development of new drugs and medicinal compounds.
Used in Research and Development:
In research and development settings, 1-(P-Tosyl)-3,4,4-trimethyl-2-imidazolinium iodide is used as a catalyst to explore new reaction pathways and develop innovative synthetic methods. Its versatility and stability under various reaction conditions make it an essential component in advancing the field of organic chemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 71254-91-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,1,2,5 and 4 respectively; the second part has 2 digits, 9 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 71254-91:
(7*7)+(6*1)+(5*2)+(4*5)+(3*4)+(2*9)+(1*1)=116
116 % 10 = 6
So 71254-91-6 is a valid CAS Registry Number.
71254-91-6Relevant articles and documents
MODELS OF FOLATE COENZYMES-VII SYNTHESIS AND CARBON TRANSFER REACTIONS OF N5,N10-METHENYL AND N5,N10-METHYLENETETRAHYDROFOLATE MODELS
Bieraeugel, H.,Plemp, R.,Hiemstra, H. C.,Pandit, U. K.
, p. 3971 - 3980 (2007/10/02)
Carboxylate esters react with 1,2-diaminoethanes to yield imidazolines, which upon consecutive reaction with acetic anhydride or tosyl chloride and methyl iodide give imidazolinium salts that serve as models of N5,N10-(CH+)-tetrahydrofolate (THF) coenzymes (7a,b and 18a,b).Reduction of the latter salts with sodium borohydride or reaction with anions (R-) give the corresponding 5,10--THF models.Mono- and bifunctional nucleophiles react with 18a,b to yield carbon-transfer products. 6-Alkylamino-1,3-dimethyluracils react with 1-tosyl-3,4,4-trimethylimidazolidine (the reduction product of 18b), in the presence of acetic acid, to form carbon-transfer products via a mechanism which bears close analogy to the mechanism of action of thymidylate synthetase.