7146-68-1 Usage
Description
4-(4-chlorophenyl)sulfonylaniline, also known as 4-Amino-4'-chlorodiphenyl sulfone, is a chemical compound belonging to the class of substituted 4-aminodiphenylsulfones. It is characterized by the presence of a chlorophenyl group attached to a sulfonyl group, which is further connected to an aniline moiety. 4-(4-chlorophenyl)sulfonylaniline exhibits specific chemical properties that make it suitable for various applications in different industries.
Uses
Used in Pharmaceutical Industry:
4-(4-chlorophenyl)sulfonylaniline is used as an active pharmaceutical ingredient (API) for its role as an Escherichia coli dihydropteroate synthase inhibitor. This application is significant because it helps in the development of drugs that target and inhibit the growth of E. coli bacteria, which is a common cause of various infections. By inhibiting the enzyme dihydropteroate synthase, this compound can effectively disrupt the bacterial cell's synthesis of folic acid, thereby hindering their growth and proliferation.
Check Digit Verification of cas no
The CAS Registry Mumber 7146-68-1 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 7,1,4 and 6 respectively; the second part has 2 digits, 6 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 7146-68:
(6*7)+(5*1)+(4*4)+(3*6)+(2*6)+(1*8)=101
101 % 10 = 1
So 7146-68-1 is a valid CAS Registry Number.
InChI:InChI=1/C12H10ClNO2S/c13-9-1-5-11(6-2-9)17(15,16)12-7-3-10(14)4-8-12/h1-8H,14H2
7146-68-1Relevant articles and documents
Optimization of a urea-containing series of nicotinamide phosphoribosyltransferase (NAMPT) activators
Pinkerton, Anthony B.,Sessions, E. Hampton,Hershberger, Paul,Maloney, Patrick R.,Peddibhotla, Satyamaheshwar,Hopf, Meghan,Sergienko, Eduard,Ma, Chen-Ting,Smith, Layton H.,Jackson, Michael R.,Tanaka, Jun,Tsuji, Takashi,Akiu, Mayuko,Cohen, Steven E.,Nakamura, Tsuyoshi,Gardell, Stephen J.
, (2021/04/27)
NAD+ is a crucial cellular factor that plays multifaceted roles in wide ranging biological processes. Low levels of NAD+ have been linked to numerous diseases including metabolic disorders, cardiovascular disease, neurodegeneration,
EFFECT OF INHIBITORS OF RADICAL-ION CHAIN PROCESSES ON THE AMMONOLYSIS OF DI(4-CHLOROPHENYL) SULFONE
Sosonkin, I. M.,Novokhatka, D. A.,Lakomova, N. A.,Golikova, A. V.,Ponomareva, T. K.,et al.
, p. 209 - 210 (2007/10/02)
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