7149-70-4 Usage
Description
2-Bromo-5-nitrotoluene is an organic compound that features a bromine atom at the 2nd position and a nitro group at the 5th position on a toluene ring. It is a versatile intermediate in organic synthesis and possesses unique chemical properties due to the presence of both bromine and nitro groups.
Uses
Used in Chemical Synthesis:
2-Bromo-5-nitrotoluene is used as a synthetic intermediate for the production of various organic compounds. Its unique structure allows it to participate in a range of chemical reactions, making it a valuable building block in the synthesis of pharmaceuticals, agrochemicals, and other specialty chemicals.
Used in the Synthesis of 4′-amino-4-hydroxy-2′-methylbiphenyl:
2-Bromo-5-nitrotoluene is used as a key reactant in the synthesis of 4′-amino-4-hydroxy-2′-methylbiphenyl through a condensation reaction with potassium m-nitrophenoxide. This reaction showcases the compound's reactivity and its potential use in the development of novel organic molecules with specific applications.
Additionally, 2-Bromo-5-nitrotoluene is utilized in the synthesis of 3′:4-dinitro-2-methyldiphenyl ether, another complex organic molecule. This further demonstrates the compound's versatility and its role in creating a diverse range of chemical products.
Check Digit Verification of cas no
The CAS Registry Mumber 7149-70-4 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 7,1,4 and 9 respectively; the second part has 2 digits, 7 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 7149-70:
(6*7)+(5*1)+(4*4)+(3*9)+(2*7)+(1*0)=104
104 % 10 = 4
So 7149-70-4 is a valid CAS Registry Number.
InChI:InChI=1/C7H6BrNO2/c1-5-4-6(9(10)11)2-3-7(5)8/h2-4H,1H3
7149-70-4Relevant articles and documents
Nitration of deactivated aromatic compounds via mechanochemical reaction
Wu, Jian-Wei,Zhang, Pu,Guo, Zhi-Xin
supporting information, (2021/05/05)
A variety of deactivated arenes were nitrated to their corresponding nitro derivatives in excellent yields under high-speed ball milling condition using Fe(NO3)3·9H2O/P2O5 as nitrating reagent. A radical involved mechanism was proposed for this facial, eco-friendly, safe, and effective nitration reaction.
PROTON TRANSFER REACTIONS BETWEEN ORTHO-METHYL SUBSTITUTED DERIVATIVES OF 4-NITROPHENYLPHENYLCYANOMETHANE AND NITROGEN BASES IN ACETONITRILE SOLVENT
Leffek, Kenneth T.,Pruszynski, Przemyslaw
, p. 1454 - 1458 (2007/10/02)
Equilibrium constants, rate constants, primary deuterium isotope effects, and activation parameters have been measured for the proton transfer reactions in acetonitrile solvent of 4-nitrophenylphenylcyanomethane and 2-methyl-4-nitrophenylphenylcyanomethane with tetramethylguanidine base and for the reactions of 2-methyl-4-nitrophenylphenylcyanomethane and 2,6-dimethyl-4-nitrophenylphenylcaynomethane with 1,5-diazabicycloundec-7-ene base.Introduction of the ortho-methyl groups in the substrate molecule caused significant reductions in the equilibrium and the rate constants.The expected rise in the kinetic primary deuterium isotope effect was not observed when the first ortho-methyl group was introduced, but a 20percent increase did accompany the introduction of the second ortho-methyl group.Enthalpy of activation measurements indicated that there was no increase in the proton tunnelling contribution to the isotope effect when the amount of steric hindrance is increased with ortho-methyl groups.