7149-77-1

Basic information

• Product Name: 1,5-Dichloro-2-methyl-4-nitrobenzene
• Synonyms: 1,5-Dichloro-2-methyl-4-nitrobenzene;2,4-DICHLORO-5-NITROTOLUENE
• CAS NO: 7149-77-1
• Molecular Formula: C₇H₅Cl₂NO₂
• Molecular Weight: 206.03
• Mol File: 7149-77-1.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 296.3°C at 760 mmHg
• Flash Point: 133°C
• Appearance: /
• Density: 1.456g/cm³
• Vapor Pressure: 0.00256mmHg at 25°C
• Refractive Index: 1.585
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 1,5-Dichloro-2-methyl-4-nitrobenzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1,5-Dichloro-2-methyl-4-nitrobenzene(7149-77-1)
• EPA Substance Registry System: 1,5-Dichloro-2-methyl-4-nitrobenzene(7149-77-1)

Safety Data

• Hazardous Substances Data: 7149-77-1(Hazardous Substances Data)

Usage

Description

1,5-Dichloro-2-methyl-4-nitrobenzene, an aromatic chemical compound with the molecular formula C7H5Cl2NO2, is a yellow crystalline solid that is insoluble in water but soluble in organic solvents. It is commonly used as an intermediate in the synthesis of various chemicals, including pharmaceuticals, dyes, and agrochemicals.

Uses

Used in Pharmaceutical Industry:
1,5-Dichloro-2-methyl-4-nitrobenzene is used as a chemical intermediate for the synthesis of various pharmaceuticals. Its unique structure allows for the development of new drugs with potential therapeutic applications.
Used in Dye Industry:
In the dye industry, 1,5-Dichloro-2-methyl-4-nitrobenzene is utilized as a precursor in the production of various dyes. Its chemical properties enable the creation of dyes with specific color characteristics and stability.
Used in Agrochemical Industry:
1,5-Dichloro-2-methyl-4-nitrobenzene is employed as a starting material in the synthesis of agrochemicals, such as pesticides and herbicides. Its reactivity and functional groups contribute to the development of effective and targeted agrochemical products.
Safety Precautions:
Due to its hazardous properties, 1,5-Dichloro-2-methyl-4-nitrobenzene should be handled with care and in accordance with proper safety protocols. Appropriate personal protective equipment, such as gloves and safety goggles, should be worn during handling, and the compound should be stored in a well-ventilated area away from heat and open flames.

InChI:InChI=1/C7H5Cl2NO2/c1-4-2-7(10(11)12)6(9)3-5(4)8/h2-3H,1H3

Upstream product

• 95-73-8 2,4-dichlorotoluene 
• 7149-80-6 5-chloro-4-methyl-2-nitroaniline 
• 13852-51-2 5-chloro-2-methyl-4-nitroaniline 

Downstream Products

• 50342-31-9 1,5-dimethoxy-2-methyl-4-nitrobenzene 
• 36860-15-8 2,4-dichloro-3,5-dinitro-toluene 
• 100777-46-6 1-chloro-5-methoxy-2-methyl-4-nitrobenzene 
• 108-44-1 1-amino-3-methylbenzene 
• 17601-75-1 2,4-dichloro-5-methyl-aniline 
• 65273-37-2 2-[[2-(5-Chloro-4-methyl-2-nitro-phenylamino)-ethyl]-(2-hydroxy-ethyl)-amino]-ethanol 
• 56223-82-6 N'-(5-Chloro-4-methyl-2-nitro-phenyl)-N,N-diethyl-ethane-1,2-diamine 
• 7149-80-6 5-chloro-4-methyl-2-nitroaniline 
• 67007-75-4 1-(5-chloro-4-methyl-2-nitro-anilino)-D-1-deoxy-ribitol 
• 265662-24-6 5-chloro-N-isobutyl-4-methyl-2-nitroaniline 
• 649763-40-6 2-amino-5-chloro-N⁽¹⁾-isobutyl-4-methylaniline 
• 265662-30-4 (5-ethynyl-4-methyl-2-nitro-phenyl)-isobutyl-amine 
• 265662-27-9 {5-[(tert-butyl-dimethyl-silanyl)-ethynyl]-4-methyl-2-nitro-phenyl}-isobutyl-amine 
• 57046-02-3 acetic acid-(2,4-dichloro-5-methyl-anilide) 

Relevant articles and documents

Preparation method of dichlorotoluene nitride intermediate

The invention belongs to the technical field of preparation of pesticide intermediates, and particularly discloses a preparation method of a dichlorotoluene nitride intermediate. The preparation method comprises the following steps: fully reacting raw materials, a solvent and a nitration reagent to obtain a dichlorotoluene nitride intermediate, wherein the raw materials comprise any one of o-dichlorotoluene, m-dichlorotoluene and p-dichlorotoluene; the solvent is dichloroethane; the nitration reagent is concentrated nitric acid; the dichlorotoluene nitride intermediate is shown as a chemical formula 7 and a chemical formula 12. The preparation method has the advantages that the corrosion to reaction equipment is less, and the generation and discharge of waste acid and waste salt in the production process are greatly reduced.

Model Systems for Flavoenzyme Activity: Relationships between Cofactor Structure, Binding and Redox Properties

A series of flavins were synthesized bearing electron-withdrawing and -donating substituents. The electrochemical properties of these flavins in a nonpolar solvent were determined. The recognition of these flavins by a diamidopyridine (DAP) receptor and the effect this receptor has on flavin redox potential was also quantified. It was found that the DAP-flavin binding affinity and the reduction potentials (E1/2) for both the DAP-bound and unbound flavins correlated well with functions derived from linear free energy relationships (LFERs). These results provide insight and predictive capability for the interplay of electronics and redox state-specific interactions for both abiotic and enzymatic systems.

Herbicidal triazolinones

A herbicidal compound which is a Q-substituted 1-aryl-4,5-dihydro-1,2,4-triazol-5(1H)-one in which the Q-substituent is on the ring-carbon atom at the 5-position of the aryl group and in which: Q is (a) --CH(R1)ZR in which Z is O or S(O)n and n is zero, one or two; or (b) --CH(R1)N(R4)(R5); or (c) --C(R9)=NR6 ; or STR1