7154-49-6 Usage
Description
1-(1H-1,2,4-triazol-5-yl)urea is a chemical compound characterized by the molecular formula C3H4N4O. It is a derivative of urea, featuring a triazole ring in its structure. 1-(1H-1,2,4-triazol-5-yl)urea is known for its potential applications in various fields due to its unique chemical properties.
Uses
Used in Pharmaceutical Industry:
1-(1H-1,2,4-triazol-5-yl)urea is used as an intermediate in the synthesis of pharmaceuticals. Its unique structure allows it to be a key component in the development of new drugs, particularly those with antifungal and antimicrobial properties.
Used in Agrochemical Industry:
1-(1H-1,2,4-triazol-5-yl)urea is also utilized as an intermediate in the synthesis of agrochemicals. Its ability to inhibit the growth of certain plant pathogens makes it a potential candidate for the development of new crop protection agents.
Used in Antifungal Applications:
Due to its antifungal properties, 1-(1H-1,2,4-triazol-5-yl)urea is used as an active ingredient in the development of antifungal agents. These agents can be employed to combat fungal infections in various settings, including medical and agricultural applications.
Used in Antimicrobial Applications:
1-(1H-1,2,4-triazol-5-yl)urea's antimicrobial properties make it a valuable compound for the development of antimicrobial agents. These agents can be used to inhibit the growth of harmful microorganisms, contributing to improved hygiene and reduced risk of infection in various industries.
Used in Crop Protection:
1-(1H-1,2,4-triazol-5-yl)urea's potential use in crop protection is due to its ability to inhibit the growth of certain plant pathogens. This makes it a promising compound for the development of new products aimed at protecting crops from diseases and improving overall agricultural productivity.
Further research is necessary to fully understand the potential applications and properties of 1-(1H-1,2,4-triazol-5-yl)urea, as its unique structure and properties offer promising avenues for exploration in various industries.
Check Digit Verification of cas no
The CAS Registry Mumber 7154-49-6 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 7,1,5 and 4 respectively; the second part has 2 digits, 4 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 7154-49:
(6*7)+(5*1)+(4*5)+(3*4)+(2*4)+(1*9)=96
96 % 10 = 6
So 7154-49-6 is a valid CAS Registry Number.
7154-49-6Relevant articles and documents
Synthesis of N4-amino and N4-hydroxy derivatives of 5-azacytidine. A facile rearrangement of the N4-amino derivative to 5-(3-β-D-ribofuranosylureido)-1H-1,2,4-triazole
Piskala, Alois,Hanna, Naeem B.,Masojidkova, Milena,Fiedler, Pavel,Votruba, Ivan
, p. 905 - 917 (2007/10/03)
Treatment of methoxyribosyltriazinone 4 with hydrazine in methanol afforded crude 4-hydrazino-1-β-D-ribofuranosyl-1,3,5-triazin-2(1H)-one (N 4-amino-5-azacytidine) (2), which rearranged rapidly to isomeric 5-ribosylureidotriazole 6. The rearrangement proceeds easily also in water solutions of 2. Alkaline hydrolysis of 6 gave a mixture of 5-ureidotriazole 7 and 5-aminotriazole 8. Acid hydrolysis of 6 afforded only 7. This compound was also prepared by thermal rearrangement of 5-amino-1-carbamoyltriazole 9 or on reaction of cyano(formyl)guanidine 10 with hydrazine hydrochloride. Treatment of benzoylated methoxyribosyltriazinone 4a with hydrazine in methanol gave only the rearranged product 6a. Reaction of tribenzoylribosyl isocyanate 12 with aminotriazole 8 gave 1-triazolecarboxamidotribenzoylribose 13, which afforded by methanolysis oxazoloribofuranose 14 and aminotriazole 8. Compound 14 was also obtained by methanolysis of blocked ribosylcarbamate 16. Reaction of methoxyribosyltriazinone 4 with hydroxylamine in methanol afforded 4-hydroxylamino-1-β-D-ribofuranosyl-1,3,5-triazin-2(1H)-one (N 4-hydroxy-5-azacytidine) (3), which on the action of excess hydroxylamine yielded 1-cyano-1-hydroxy-5-β-D-ribofuranosylisobiuret (19). Treatment of methoxy-1,3,5-triazinone 18 with a solution of hydroxylamine in methanol gave 4-hydroxylamino-1-methyl-1,3,5-triazin-2(1H)-one (N 4-hydroxy1-methyl-5-azacytosine) (17). Heating of cyano(formyl)guanidine 10 with hydroxylamine hydrochloride in water lead to the formation of triuret (21). The mechanisms of the reactions of methoxyribosyltriazinone 4 with hydrazine and hydroxylamine are discussed. Compounds 2, 6 and 19 exhibited no significant antibacterial or cytostatic activity.
