72142-97-3

Basic information

• Product Name: 8-methoxythionepsoralen
• Synonyms: 8-methoxythionepsoralen
• CAS NO: 72142-97-3
• Molecular Formula: C12H8 O3 S
• Molecular Weight: 232.26
• Mol File: 72142-97-3.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 373.4°C at 760 mmHg
• Flash Point: 179.6°C
• Appearance: /
• Density: 1.42g/cm³
• Vapor Pressure: 1.93E-05mmHg at 25°C
• Refractive Index: 1.708
• CAS DataBase Reference: 8-methoxythionepsoralen(CAS DataBase Reference)
• NIST Chemistry Reference: 8-methoxythionepsoralen(72142-97-3)
• EPA Substance Registry System: 8-methoxythionepsoralen(72142-97-3)

Safety Data

• Hazardous Substances Data: 72142-97-3(Hazardous Substances Data)

Usage

InChI:InChI=1/C12H8O3S/c1-13-12-10-8(4-5-14-10)6-7-2-3-9(16)15-11(7)12/h2-6H,1H3

Upstream product

• 298-81-7 9-methoxy-7H-furo[3,2-g][1]benzopyran-7-one 

Relevant articles and documents

Microwave-accelerated solvent-free synthesis of thioketones, thiolactones, thioamides, thionoesters, and thioflavonoids

Formula presented An expeditious, solvent-free, and high yield conversion of ketones, flavones, isoflavones, lactones, amides, and esters to the corresponding thio analogues is described utilizing Lawesson's reagent in a process that circumvents the use of dry solvents and excess of the reagent.

PHOTOBIOLOGICAL PROPERTIES OF FUROTHIOCOUMARINS IN SACCHAROMYCES CEREVISIAE

Nine furothiocoumarins corresponding to psoralen, 8-methylpsoralen, 3-carbethoxy-8-methylpsoralen, 8-methoxysporalen, pseudosporalen, angelicin, isopseudosporalen, allopsoralen and pseudoisosporalen were synthesized by treating furocoumarins with phosphorus pentasulfide. Photobiological studies on haploid yeast cells (Saccharomyces cerevisiae) revealed that the furocoumarins exert some photoactivity on cell survival and the induction of mitochondrial damage.In most cases, the furothiocoumarins were less active than their furocoumarinic counterparts and exhibited a preference for a monofunctional type of action.A certain photochemotherapeutic activity can be suggested.