72180-45-1

Basic information

• Product Name: 2(1H)-Quinolinone, 3,4-dihydro-6-[4-(phenylsulfinyl)butoxy]-
• CAS NO: 72180-45-1
• Molecular Formula: C19H21NO3S
• Molecular Weight: 343.447
• Mol File: 72180-45-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2(1H)-Quinolinone, 3,4-dihydro-6-[4-(phenylsulfinyl)butoxy]-(CAS DataBase Reference)
• NIST Chemistry Reference: 2(1H)-Quinolinone, 3,4-dihydro-6-[4-(phenylsulfinyl)butoxy]-(72180-45-1)
• EPA Substance Registry System: 2(1H)-Quinolinone, 3,4-dihydro-6-[4-(phenylsulfinyl)butoxy]-(72180-45-1)

Safety Data

• Hazardous Substances Data: 72180-45-1(Hazardous Substances Data)

Upstream product

• 110-52-1 1,4-dibromo-butane 
• 54197-66-9 3,4-dihydro-6-hydroxy-2(1H)-quinolinone 
• 108-98-5 thiophenol 

Downstream Products

• 72180-47-3 6-(4-phenylsulfonyl-butoxy)-3,4-dihydro-carbostyril 

Relevant articles and documents

Cardiotonic and antithrombotic sulfur-containing derivatives of carbostyril

Compounds of the formula STR1 wherein W is vinylene, methyl-vinylene, methylene or ethylene; m is 0, 1 or 2; D is straight or branched alkylene of 2 to 6 carbon atoms, straight or branched hydroxy-alkylene of 3 to 6 carbon atoms, or xylylene; R1 is hydrogen or alkyl of 1 to 3 carbon atoms; R2 is cycloalkyl of 3 to 6 carbon atoms, aryl of 6 to 10 carbon atoms, aralkyl of 7 to 11 carbon atoms, heteroaryl, heteroarlkyl, 1,2,4-triazolyl, triphenylmethyl, 4,5-bis-(p-chlorophenyl)-oxazol-2-yl, N-methyl-cyclohexylamino-carbonylmethyl,-amino-iminomethyl or, when m is 1 or D is hydroxyalkylene or xylylene, also alkyl of 1 to 6 carbon atoms; and R3 and R4 are each hydrogen, halogen, alkyl of 1 to 4 carbon atoms, amino, acetylamino or nitro. The compounds of the invention are useful as cardiotonics and as antithrombotics.