72395-46-1

Basic information

• Product Name: N,N-diethyl-1H-indole-1-ethylamine
• Synonyms: N,N-diethyl-1H-indole-1-ethylamine;N,N-Diethyl-1H-indole-1-ethanamine
• CAS NO: 72395-46-1
• Molecular Formula: C14H20N2
• Molecular Weight: 216.322
• EINECS: 276-637-5
• Mol File: 72395-46-1.mol
• Article Data: 332

Chemical Properties

• Boiling Point: 331.5°C at 760 mmHg
• Flash Point: 154.3°C
• Appearance: /
• Density: 0.97g/cm³
• Vapor Pressure: 0.000156mmHg at 25°C
• Refractive Index: 1.542
• PKA: 10.24±0.25(Predicted)
• CAS DataBase Reference: N,N-diethyl-1H-indole-1-ethylamine(CAS DataBase Reference)
• NIST Chemistry Reference: N,N-diethyl-1H-indole-1-ethylamine(72395-46-1)
• EPA Substance Registry System: N,N-diethyl-1H-indole-1-ethylamine(72395-46-1)

Safety Data

• Hazardous Substances Data: 72395-46-1(Hazardous Substances Data)

Usage

General Description

N,N-diethyl-1H-indole-1-ethylamine, also known as 1-(1H-indol-1-yl)ethan-1-amine, is a chemical compound with the molecular formula C16H20N2. It is a derivative of indole and ethylamine, and it is commonly used as an intermediate in the synthesis of various pharmaceuticals and organic compounds. N,N-diethyl-1H-indole-1-ethylamine has been studied for its potential applications in the treatment of neurological disorders and as a precursor for the production of drugs with psychotropic effects. N,N-diethyl-1H-indole-1-ethylamine is also known for its role in the synthesis of various alkaloids and as a component in research on the pharmacological properties of indole derivatives. Overall, this chemical compound has significant potential for applications in pharmaceutical and research fields.

InChI:InChI=1/C14H20N2/c1-3-15(4-2)11-12-16-10-9-13-7-5-6-8-14(13)16/h5-10H,3-4,11-12H2,1-2H3

Upstream product

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• 75-79-6 Methyltrichlorosilane 
• 74-87-3 methylene chloride 
• 34557-54-5 methane 
• 7787-87-3 (1-chloroethyl)trimethylsilane 
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• 14629-58-4 trimethyl(phenethyloxy)silane 
• 75-16-1 methylmagnesium bromide 
• 98-13-5 Phenyltrichlorosilane 
• 768-33-2 phenyldimethylsilyl chloride 
• 60-29-7 diethyl ether 

Relevant articles and documents

4? + 2? Cycloadditions to P-Chlorobis(trimethylsilyl)methylenephosphine: New Cyclic Compounds with a >C=P-Double Bond

The reaction of P-chlorobis(trimethylsilyl)methylenephosphine with several 1,3-dipoles and two dienes gives cycloadducts regiospecifically, these will eliminate Me3SiCl at low temperatures if the resulting compound is of an 'aromatic' type, leading to new cyclic >C=P- double bond derivatives.

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Preparation and Crystal Structure of Cu4iP-CH2-PPri2>Cl3(Py)2 (Py=pyridine): A Novel Copper Complex with a Triply Bridging Secondary Phosphido Group μ-PRR' i; R'=CH2-PPri2>

The first copper complex Cu4(PriP-CH2-PPri2)Cl3(Py)2 (Py=pyridine) containing a triply bridging secondary phosphido group μ-PRR' has been synthesized and characterized by X-ray crystallography.

A NOVEL APPROACH TO THE SYNTHESIS OF DEOXYNUCLEOSIDE PHOSPHOROFLUORIDATES - II.

Trimethylsilyl esters of general formula RR'POSiMe3 derived from nucleosides react in quantitative and fully chemoselective way with sulphuryl chloride fluoride to give nucleoside fluorophosphates of high purity under extremely mild conditions

Intramolecular base-stabilised adducts of main group halides

The coordination chemistry of alkoxo and amido ligands bearing pendant nitrogen or sulfur donors has been developed to include examples of main group complexes. The structural implications of amido ligand coordination augmented by a tethered pyridyl base have been investigated for group 13 and 14 derivatives {[6-(Me3SiN)-2-Me-C5H3N]SnCl3 and [6-(Me3SiN)-2-Me-C5H3N]BBr2}. Furthermore, the scope, kinetics and mechanism of the synthesis of alkoxo and amido derivatives from trimethylsilyl substituted precursors have been investigated in depth. The methodology is found to be applicable to a range of ligand frameworks of varying flexibility, stabilised by one or two "tether" arms.

Triplet-state photoreactivity of phenyldisilanes

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Reaction of alkali metal dibutylboron with alkyl halides in diethyl ether solution

The reaction of alkali metal dibutylboron (I), prepared by the treatment of dibutylchloroborane with sodium/potassium alloy in diethyl ether, with alkyl iodides has been studied. Very little alkylation on boron to produce dibutylalkylborane occurs in ethe

Reactions of N,N′-dimethyl-N,N′-bis(trimethylsilyl)-methylphosphonic diamide with chloral and chloromethyldimethylchlorosilane

N,N′-Dimethyl-N,N′-bis(trimethylsilyl)methylphosphonic diamide reacts with chloral to form 1,2,3-trimethyl-4,4-dichloro-5-trimethylsiloxy-1,3,2-diazaphospholidine 2-oxide and with chloromethyldimethylchlorosilane to form 1,2,3,4,4-pentamethyl-1,3-diaza-2-

A General and Selective Synthesis of Methylmonochlorosilanes from Di-, Tri-, and Tetrachlorosilanes

Direct catalytic transformation of chlorosilanes into organosilicon compounds remains challenging due to difficulty in cleaving the strong Si-Cl bond(s). We herein report the palladium-catalyzed cross-coupling reaction of chlorosilanes with organoaluminum reagents. A combination of [Pd(C3H5)Cl]2 and DavePhos ligand catalyzed the selective methylation of various dichlorosilanes 1, trichlorosilanes 5, and tetrachlorosilane 6 to give the corresponding monochlorosilanes.

METHOD FOR PRODUCING HALOSILANE

PROBLEM TO BE SOLVED: To provide a method for producing halosilane that can efficiently produce halosilane. SOLUTION: Alkoxy halomethane is used as a halogenating agent and reacted with oxysilane having a structure represented by formula (a), to efficiently produce halosilane having a structure represented by formula (b) (In the formula (b), X is a chlorine atom, a bromine atom, or an iodine atom). SELECTED DRAWING: None COPYRIGHT: (C)2019,JPOandINPIT

SYNTHESIS OF ORGANO CHLOROSILANES FROM ORGANOSILANES

The invention relates to a process for the production of chlorosilanes by subjecting one or more hydndosilanes to the reaction with hydrogen chloride in the presence of at least one ether compound, and a process for the production of such hydndosilanes serving as starting materials.