728944-91-0

Basic information

• Product Name: (R)-tert-butyl 2-{[(benzyloxy)carbonyl]amino}-3-(4-methoxyphenyl)propionate
• Synonyms: (R)-tert-butyl 2-{[(benzyloxy)carbonyl]amino}-3-(4-methoxyphenyl)propionate
• CAS NO: 728944-91-0
• Molecular Weight: 385.46
• Mol File: 728944-91-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (R)-tert-butyl 2-{[(benzyloxy)carbonyl]amino}-3-(4-methoxyphenyl)propionate(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-tert-butyl 2-{[(benzyloxy)carbonyl]amino}-3-(4-methoxyphenyl)propionate(728944-91-0)
• EPA Substance Registry System: (R)-tert-butyl 2-{[(benzyloxy)carbonyl]amino}-3-(4-methoxyphenyl)propionate(728944-91-0)

Safety Data

• Hazardous Substances Data: 728944-91-0(Hazardous Substances Data)

Upstream product

• 65806-89-5 (R)-2-{[(benzyloxy)carbonyl]amino}-3-(4-methoxyphenyl)propionic acid 
• 75-65-0 tert-butyl alcohol 
• 64205-12-5 N-α-benzyloxycarbonyl-D-tyrosine 

Downstream Products

• 162465-18-1 (S)-2-((R)-3-Amino-2-methyl-propionyloxy)-4-methyl-pentanoic acid (E)-(1S,2R)-1-{(E)-3-[(R)-1-carboxy-2-(4-methoxy-phenyl)-ethylcarbamoyl]-allyl}-2-methyl-4-phenyl-but-3-enyl ester 
• 728944-93-2 (2S,1''S,2''R,1''''R)-1''-[3'''-({1''''-[(tert-butoxy)carbonyl]-2''''-(p-methoxyphenyl)ethyl}carbamoyl)allyl]-2''-methyl-4''-phenylbut-3''-enyl 2-[(3'-{[(tert-butoxy)carbonyl]amino}propionyl)oxy]-4-methylpentanoate 
• 281191-03-5 (2S,2'R,1''S,2''R,1''''R)1''-(3'''-{1''''-[(tert-butoxy)carbonyl]-2''''-p-methoxyphenylethylcarbamoyl}allyl)-2''-methyl-4''-phenylbut-3''-enyl 2-[(3'-{[(tert-butoxy)carbonyl]amino}-2'-methylpropionyl)oxy]-4-methylpentanoate 
• 281191-01-3 (2R,2'E,5'S,6'R,7'E)-tert-butyl 3-(4-methoxyphenyl)-2-({6'-methyl-8'-phenyl-5'-[(triisopropylsilanyl)oxy]octa-2',7'-dienoyl}amino)propionate 
• 281191-02-4 (2R,2'E,5'S,6'R,7'E)-tert-butyl 2-[(5'-hydroxy-6'-methyl-8'-phenylocta-2',7'-dienoyl)amino]-3-(4-methoxyphenyl)propionate 
• 162600-54-6 cryptophycin-24 
• 162473-78-1 desepoxyarenastatin A 
• 155645-51-5 Cryptophycin 4 
• 281190-95-2 (R)-tert-butyl 2-amino-3-(4-methoxyphenyl)propionate 

Relevant articles and documents

Asymmetric syntheses of potent antitumor macrolides cryptophycin B and arenastatin A

Efficient and highly stereoselective syntheses of cryptophycin B and arenastatin A, potent cytotoxic agents, are described. An ester-derived titanium enolate mediated syn-aldol reaction was employed to generate the stereocenters C-5 and C-6. The route is convergent and provides a convenient access to the synthesis of structural variants of cryptophycins as well as members of its family. ( Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2004).