73081-72-8

Basic information

• Product Name: 2H-Pyrrol-2-one, 1,5-dihydro-1,3,5-trimethyl-4-phenyl-
• CAS NO: 73081-72-8
• Molecular Formula: C13H15NO
• Molecular Weight: 201.268
• Mol File: 73081-72-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2H-Pyrrol-2-one, 1,5-dihydro-1,3,5-trimethyl-4-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 2H-Pyrrol-2-one, 1,5-dihydro-1,3,5-trimethyl-4-phenyl-(73081-72-8)
• EPA Substance Registry System: 2H-Pyrrol-2-one, 1,5-dihydro-1,3,5-trimethyl-4-phenyl-(73081-72-8)

Safety Data

• Hazardous Substances Data: 73081-72-8(Hazardous Substances Data)

Upstream product

• 34757-17-0 ethyl 2,2-dibromopropanoate 
• 16735-30-1 2-(N-benzyl-N-methylamino)-1-phenylpropan-1-one 

Relevant articles and documents

Heteroatom-guided torquoselective olefination of α-oxy and α-amino ketones via ynolates

Ynolates were found to react with α-alkoxy-, α-siloxy-, and α -aryloxyketones at room temperature to afford tetrasubstituted olefins with high Z selectivity. Since the geometrical selectivity was determined in the ring opening of the β-lactone enolate intermediates, the torquoselectivity was controlled by the ethereal oxygen atoms. From experimental and theoretical studies, the high Z selectivity is in duced by orbital and steric interactions rather than by chelation. In a similar manner, α-dialkylamino ketones provided olefins with excellent Z selectivity. These products can be easily converted into multisubstituted butenolides and γ-butyrolactams in good yield.