73096-42-1 Usage
Description
5-(2-BROMOPHENYL)-1H-TETRAZOLE is a 5-substituted 1H-tetrazole, which is a heterocyclic compound with a chemical structure that features a tetrazole ring fused to a bromophenyl group. It is a white to off-white powder and can be synthesized through a silica-supported sulfuric acid catalyzed [3+2] cycloaddition of nitriles and sodium azide. Additionally, it has been reported to participate in copper-catalyzed reactions with ethyl 2-cyanoacetate, yielding ethyl 1,3-diaminoisoquinoline-4-carboxylate.
Uses
Used in Pharmaceutical Industry:
5-(2-BROMOPHENYL)-1H-TETRAZOLE is used as an intermediate in the synthesis of various pharmaceutical compounds. Its unique chemical structure allows it to be a valuable building block for the development of new drugs, particularly those targeting specific biological receptors or enzymes.
Used in Chemical Research:
In the field of chemical research, 5-(2-BROMOPHENYL)-1H-TETRAZOLE serves as a key compound for studying the reactivity and properties of tetrazole-based molecules. Its synthesis and subsequent reactions can provide insights into the development of new synthetic methods and the exploration of novel chemical transformations.
Used in Material Science:
5-(2-BROMOPHENYL)-1H-TETRAZOLE may also find applications in material science, particularly in the development of new materials with specific properties. Its incorporation into polymers or other materials could potentially lead to the creation of materials with enhanced thermal stability, chemical resistance, or other desirable characteristics.
Used in Agrochemical Industry:
In the agrochemical industry, 5-(2-BROMOPHENYL)-1H-TETRAZOLE could be utilized as a starting material for the synthesis of new pesticides or other agrochemicals. Its unique structure may contribute to the development of more effective and targeted products for crop protection and management.
Used in Dye and Pigment Industry:
The chemical properties of 5-(2-BROMOPHENYL)-1H-TETRAZOLE make it a potential candidate for use in the dye and pigment industry. Its synthesis and modification could lead to the development of new dyes or pigments with improved color properties, stability, or application performance.
Check Digit Verification of cas no
The CAS Registry Mumber 73096-42-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,3,0,9 and 6 respectively; the second part has 2 digits, 4 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 73096-42:
(7*7)+(6*3)+(5*0)+(4*9)+(3*6)+(2*4)+(1*2)=131
131 % 10 = 1
So 73096-42-1 is a valid CAS Registry Number.
InChI:InChI=1/C7H4BrN4/c8-6-4-2-1-3-5(6)7-9-11-12-10-7/h1-4H/q-1
73096-42-1Relevant articles and documents
Synthesis and characterization of magnetic Fe3O4@Creatinine@Zr nanoparticles as novel catalyst for the synthesis of 5-substituted 1H-tetrazoles in water and the selective oxidation of sulfides with classical and ultrasonic methods
Ghadermazi, Mohammad,Moeini, Nazanin,Molaei, Somayeh
, (2021/12/03)
Tetrazoles and sulfoxide compounds have a wide range of applications in industries and are of great expectation to be environmentally friendly and cost-effective. This paper reports the introduction of zirconium supported on Fe3O4 na
TMSN3-Bu2Sn(OAc)2: A modified and mild reagent system for Wittenberger tetrazole-synthesis
Yoneyama, Hiroki,Oka, Naoki,Usami, Yoshihide,Harusawa, Shinya
supporting information, (2020/01/21)
Treatments of various nitriles with TMSN3 and Bu2Sn(OAc)2 at 30 °C in benzene for 60 h yielded the corresponding 5-substituted 1H-tetrazoles in good to excellent yields. This method is a mild and efficient alternative reagent system for Wittenberger tetrazole-synthesis that uses TMSN3 and Bu2SnO in toluene at high temperature (93–110 °C) for 24–72 h.
Cationic organotin cluster [t-Bu2Sn(OH)(H2O)]2 2+2OTf?-catalyzed one-pot three-component syntheses of 5-substituted 1H-tetrazoles and 2,4,6-triarylpyridines in water
Wang, Hongshe,Zhao, Weixing,Du, Juan,Wei, Fenyan,Chen, Qi,Wang, Xiaomei
, (2019/08/20)
The cationic organotin cluster [t-Bu2Sn(OH)(H2O)]2 2+2OTf? is easy to prepare and stable in air. The catalytic activity of [t-Bu2Sn(OH)(H2O)]2 2+2OTf? as a neutral organotin Lewis acid catalyst is probed through the one-pot three-component syntheses of 5-substituted 1H-tetrazoles from aldehydes, hydroxylamine hydrochloride and sodium azide, and of 2,4,6-triarylpyridines from aromatic aldehydes, substituted acetophenones and ammonium acetate. The reactions proceed well in the presence of 1?mol% of [t-Bu2Sn(OH)(H2O)]2 2+2OTf? in water and provide the corresponding 5-substituted 1H-tetrazoles and 2,4,6-triarylpyridines in good to excellent yields. The method reported has several advantages such as the catalyst being neutral, low catalyst loading and use of water as a green solvent.
