73119-35-4

Basic information

• Product Name: 2,3-bis(3,4-dimethoxybenzylidene)butanedioic acid
• Synonyms: 2,3-bis(3,4-dimethoxybenzylidene)butanedioic acid
• CAS NO: 73119-35-4
• Molecular Weight: 414.412
• Mol File: 73119-35-4.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: 2,3-bis(3,4-dimethoxybenzylidene)butanedioic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3-bis(3,4-dimethoxybenzylidene)butanedioic acid(73119-35-4)
• EPA Substance Registry System: 2,3-bis(3,4-dimethoxybenzylidene)butanedioic acid(73119-35-4)

Safety Data

• Hazardous Substances Data: 73119-35-4(Hazardous Substances Data)

Upstream product

• 42923-56-8 veratrylidene-succinic acid dimethyl ester 
• 120-14-9 3,4-dimethoxy-benzaldehyde 
• 123-25-1 succinic acid diethyl ester 
• 106-65-0 Dimethyl succinate 
• 102767-61-3 4,4'-dihydroxy-3,3'-dimethoxy-β,β'-bicinnamic acid 
• 77-78-1 dimethyl sulfate 
• 5507-27-7 3,4-dimethoxybenzylidenesuccinic acid 
• 77550-11-9 4-cis,8-cis-bis(4-hydroxy-3-methoxyphenyl)-3,7-dioxabicyclo<3.3.0>octane-2,6-dione 
• 289622-16-8 diethyl 2-(3,4-dimethoxybenzylidene)succinate 
• 126274-95-1 2-(3,4-dimethoxybenzylidene)butanedioic acid monoethyl ester 

Downstream Products

• 25936-93-0 6,7-dimethoxy-1-(3',4'-dimethoxyphenyl)naphthalene-2,3-dicarboxylic anhydride 
• 126965-32-0 meso-1,2-bis[(3,4-dimethoxyphenyl)methyl]ethane-1,2-dicarboxylic acid 
• 15813-34-0 D,L-2,3-bis(3,4-dimethoxybenzyl)succinic acid 
• 91231-60-6 2,3-bis(3,4-dimethoxybenzylidene)butanedioic acid anhydride 
• 10352-26-8 trans-3,4-bis(3,4,-dimethoxybenzyl)tetrahydrofuran 
• 876026-47-0 cis-3,4-Diveratryl-tetrahydro-furan 
• 10352-25-7 (±)-secoisolariciresinol dimethyl ether 
• 156769-15-2 meso-2,3-bis[(3,4-dimethoxyphenyl)methyl]-butane-1,4-diol 
• 5701-82-6 2,3-bis[(3,4-dimethoxyphenyl)methyl]butane 
• 103402-11-5 racem.-1,4-bis-(toluene-4-sulfonyloxy)-2,3-diveratryl-butane 
• 103402-11-5 meso-1,4-bis-(toluene-4-sulfonyloxy)-2,3-diveratryl-butane 
• 24150-24-1 terameprocol 
• 81446-31-3 (+)-O-Methyl-isoarctigenin 
• 163732-96-5 (2R,3S)-2,3-Bis-(3,4-dimethoxy-benzyl)-N-((R)-1-phenyl-ethyl)-succinamic acid 

Relevant articles and documents

Therapeutic and diagnostic ligand systems comprising transport molecule binding properties and medicaments containing the same

The invention relates to transport molecule binding ligand compounds which comprise a therapeutically and/or diagnostically active substance and a carrier molecule-affine substance with a high association constant to the carrier molecule. The invention also relates to medicaments containing these ligand compounds and to diagnostic kits.

New synthetic route to butanolide lignans by a ruthenium complex catalyzed hydrogenation of the corresponding Stobbe's fulgenic acids

A new two-step total synthesis of butanolide lignans (or dibenzylbutyrolactone lignans) is described, which affords the title compounds in good yield and with a very short work-up time. It involves a ruthenium carbonyl hydride complex-catalyzed hydrogenation of the corresponding dibenzylidene succinic acids (fulgenic acids). Since the catalytic hydrogenation (second step) is a total yielding process, the overall yield determining step is the preparation of the fulgenic acid intermediates by the Stobbe condensation (first step), which has consequently been revised to improve many details. This simple process moreover allows hexadeuterated butanolide lignans to be readily obtained for isotopic dilution mass spectral measurements. The syntheses of a selection of lignans, namely enterolactone, matairesinol, hinokinin, dimethylmatairesinol and cordigerine, are described to illustrate the whole procedure.

Nucleophilic reactivity of dehydrodiferulic acid bislactone

Despite reports to the contrary, dehydrodiferulic acid bislactone can readily undergo nucleophilic attack.Silylation affords the disilyl ether-disilyl ester of the corresponding bismethylenesuccinic acid.Slow dissolution of the bislactone in sodium hydrogen carbonate solution affords this parent diacid, characterised as its mono- and dimethyl esters, and by its methylation to bisveratrylidenesuccinic acid, whose anhydride on aerial oxidation yields 6,7-dimethoxy-1-(3',4'-dimethoxyphenyl)naphthalene-2,3-dicarboxylic anhydride.