7335-34-4

Basic information

• Product Name: Benzamide, N-hydroxy-3-nitro-
• CAS NO: 7335-34-4
• Molecular Formula: C7H6N2O4
• Molecular Weight: 182.136
• Mol File: 7335-34-4.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: Benzamide, N-hydroxy-3-nitro-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzamide, N-hydroxy-3-nitro-(7335-34-4)
• EPA Substance Registry System: Benzamide, N-hydroxy-3-nitro-(7335-34-4)

Safety Data

• Hazardous Substances Data: 7335-34-4(Hazardous Substances Data)

Upstream product

• 618-95-1 methyl 3-nitrobenzoate 
• 121-92-6 3-nitrobenzoic acid 
• 121-90-4 m-nitrobenzoic acid chloride 
• 3431-62-7 3-nitrobenzaldoxime 
• 99-61-6 3-nitro-benzaldehyde 
• 56-23-5 tetrachloromethane 
• 64-17-5 ethanol 
• 618-98-4 ethyl 3-nitrobenzoate 
• 7803-49-8 hydroxylamine 

Downstream Products

• 1356921-99-7 3-hydroxy-2-(3-nitrobenzoyl)-4-phenyl-2H-isoxazol-5-one 
• 97284-96-3 oxo hydroxo bis-(3-nitro benzhydroxamato) vanadium (V) 
• 64125-03-7 5-methoxycarbonylmethyl-3-(3-nitro-phenyl)-[1,4,2]dioxazole-5-carboxylic acid methyl ester 
• 4886-35-5 O-<3-Nitro-phenylcarbamoyl>-3-nitro-benzhydroxamsaeure 

Relevant articles and documents

HETEROCYCLIC COMPOUNDS AS KINASE INHIBITORS

Heterocyclic compounds as CDK4 or CDK6 or other CDK inhibitors are provided. The compounds may find use as therapeutic agents for the treatment of diseases and may find particular use in oncology.

Formal Lossen Rearrangement/[3+2] Annulation Cascade Catalyzed by a Modified Cyclopentadienyl RhIII Complex

It has been established that a cyclopentadienyl RhIII complex with two phenyl groups and a pendant amide moiety catalyzes the formal Lossen rearrangement/[3+2] annulation cascade of N-pivaloyl benzamides and acrylamides with alkynes leading to substituted indoles and pyrroles. Mechanistic studies revealed that this cascade reaction proceeds via not the Lossen rearrangement to form anilides or enamides but C?H bond cleavage, alkyne insertion, and the formal Lossen rearrangement.

An efficient method for the preparation of hydroxamic acids

Reactions of acyl chlorides with hydroxylamine hydrochloride and NaHCO 3 generate the corresponding hydroxamic acid products in ethyl acetate and water at room temperature for 5 min. This is a simple and efficient method to synthesize a wide range of hydroxamic acids from carboxylic acids in excellent yield and high purity after simple post-treatment without chromatographic purification. In this process, the highlights are the simple separation of products and cheaply available reagents.