736133-18-9

Basic information

• Product Name: N,N'-bis(isophthalyl)fumarate
• Synonyms: N,N'-bis(isophthalyl)fumarate
• CAS NO: 736133-18-9
• Molecular Weight: 442.339
• Mol File: 736133-18-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N,N'-bis(isophthalyl)fumarate(CAS DataBase Reference)
• NIST Chemistry Reference: N,N'-bis(isophthalyl)fumarate(736133-18-9)
• EPA Substance Registry System: N,N'-bis(isophthalyl)fumarate(736133-18-9)

Safety Data

• Hazardous Substances Data: 736133-18-9(Hazardous Substances Data)

Upstream product

• 627-63-4 fumaryl dichloride 
• 99-31-0 5-aminoisophthalic acid 

Relevant articles and documents

Cross-linked bis-hemoglobins: Connections and oxygen binding

Covalently linked pairs of cross-linked hemoglobin tetramers ("bis-tetramers", shown schematically as 6-8) were prepared by reacting hemoglobin A with tetrakis acyl phosphate esters (3-5). The effects of the link between tetramers are observed in the oxygen-binding properties of the bis-tetramers: they bind oxygen cooperatively but with Hill coefficients (n 50) lower than that of the native protein and with a high average affinity. The bis-tetramers with longer connections between tetramers show a higher n50, suggesting that steric interactions between the tetramers affect cooperativity. These results correlate to the observed reduced vasoactivity of heterogeneous solutions of oligomeric cross-linked hemoglobin tetramers.