73792-08-2

Basic information

• Product Name: METHYL 4-AMINO-2-FLUOROBENZOATE
• Synonyms: METHYL 4-AMINO-2-FLUOROBENZOATE;2-Fluoro-4-aminobenzoic acid methyl ester;Methyl 2-fluoro-4-aminobenzoate;Benzoic acid,4-aMino-2-fluoro-, Methyl ester
• CAS NO: 73792-08-2
• Molecular Formula: C₈H₈FNO₂
• Molecular Weight: 169.1530232
• Mol File: 73792-08-2.mol
• Article Data: 19

Chemical Properties

• Boiling Point: 302.319 °C at 760 mmHg
• Flash Point: 136.638 °C
• Appearance: /
• Density: 1.264 g/cm³
• Vapor Pressure: 0.001mmHg at 25°C
• Refractive Index: 1.544
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• Solubility: DMSO (Slightly), Methanol (Slightly)
• PKA: 1.45±0.10(Predicted)
• CAS DataBase Reference: METHYL 4-AMINO-2-FLUOROBENZOATE(CAS DataBase Reference)
• NIST Chemistry Reference: METHYL 4-AMINO-2-FLUOROBENZOATE(73792-08-2)
• EPA Substance Registry System: METHYL 4-AMINO-2-FLUOROBENZOATE(73792-08-2)

Safety Data

• Hazardous Substances Data: 73792-08-2(Hazardous Substances Data)

Usage

General Description

Methyl 4-amino-2-fluorobenzoate is a chemical compound with the molecular formula C8H8FNO2. It is an ester derivative of benzoic acid, containing a methyl group and an amino group. The compound also contains a fluorine atom, which gives it the characteristic of being a fluorobenzoate. Methyl 4-amino-2-fluorobenzoate is used as an intermediate in the synthesis of various pharmaceuticals and agrochemicals. It is also employed as a reagent in organic chemistry for the preparation of other compounds. Additionally, it has been studied for its potential biological activities, including its role as an antifungal agent.

InChI:InChI=1/C8H8FNO2/c1-12-8(11)6-3-2-5(10)4-7(6)9/h2-4H,10H2,1H3

Upstream product

• 403-24-7 2-fluoro-4-nitrobenzoic acid 
• 1427-07-2 2-fluoro-4-nitrotoluene 
• 67-56-1 methanol 
• 446-31-1 2-fluoro-4-aminobenzoic acid 
• 125568-77-6 methyl 4-azido-2-fluorobenzoate 
• 108-88-3 toluene 
• 109-89-7 diethylamine 
• 392-09-6 2-fluoro-4-nitro-benzoic acid methyl ester 

Downstream Products

• 959778-24-6 methyl 2-fluoro-4-{[(2-fluorophenyl)carbonyl]amino}benzoate 
• 1582286-22-3 4-acetamido-2-fluoro-N-methoxy-N-methylbenzamide 
• 1582286-23-4 N-(3-fluoro-4-propionylphenyl)acetamide 
• 1582286-26-7 C₁₁H₁₁BrFNO₂ 
• 1582286-27-8 C₁₃H₁₀F₄N₂O₂ 
• 1582286-28-9 C₁₈H₁₈F₄N₂O₄ 
• 1582286-29-0 C₁₆H₁₆F₄N₂O₃ 
• 1582286-25-6 3-fluoro-4-(5-methyl-2-(trifluoromethyl)oxazol-4-yl)aniline 
• 1582286-31-4 2,6-difluoro-N-(3-fluoro-4-(5-methyl-2-(trifluoromethyl)oxazol-4-yl)phenyl)benzamide 
• 1402586-48-4 1-[[2-(3-chlorophenyl)-5-(trifluoromethyl)-2H-pyrazol-3-yl]-methyl]-3-[3-fluoro-4-(methoxycarbonyl)-phenyl]-urea 
• 1402582-01-7 4-[[[2-(3-chlorophenyl)-5-(trifluoromethyl)-2H-pyrazol-3-yl]methylcarbamoyl]amino]-2-fluorobenzamide 
• 1402582-04-0 4-[[[2-(3-chlorophenyl)-5-(trifluoromethyl)-2H-pyrazol-3-yl]methylcarbamoyl]amino]-2-fluoro-N-(2-hydroxyethyl)benzamide 
• 1402582-03-9 4-[[[2-(3-chlorophenyl)-5-(trifluoromethyl)-2H-pyrazol-3-yl]methylcarbamoyl]amino]-2-fluoro-N,N-dimethylbenzamide 
• 1402582-08-4 4-(3-((1-(3-chlorophenyl)-3-(trifluoromethyl)-1H-pyrazol-5-yl)methyl)ureido)-2-fluorobenzoic acid 

Relevant articles and documents

DIARYLTHIOHYDANTOIN COMPOUND AS ANDROGEN RECEPTOR ANTAGONIST

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Bioorthogonal prodrug activation/decaging strategies need to be selective, rapid and release the drug from the masking group upon activation. The rates of the 1,3-dipolar cycloaddition between a trans-cyclooctene (TCO) and a series of fluorine-substituted