73873-61-7 Usage
Description
(1r,4r)-4-Methoxycyclohexane-1-carboxylic acid is a chiral organic compound with a cyclohexane ring, featuring a methoxy group and a carboxylic acid functional group. Its specific stereochemistry, with the R configuration at both the 1st and 4th positions, makes it a valuable building block in the synthesis of various pharmaceuticals and bioactive molecules.
Uses
Used in Pharmaceutical Industry:
(1r,4r)-4-Methoxycyclohexane-1-carboxylic acid is used as a reactant for the preparation of pyrazolylmethylamino isoindoline diones. These compounds act as cereblon binders, which are crucial for the degradation of Ikaros, a protein involved in various diseases. This makes (1r,4r)-4-Methoxycyclohexane-1-carboxylic acid an important component in the development of novel therapeutic agents for the treatment of diseases where Ikaros dysregulation plays a role.
Check Digit Verification of cas no
The CAS Registry Mumber 73873-61-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,3,8,7 and 3 respectively; the second part has 2 digits, 6 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 73873-61:
(7*7)+(6*3)+(5*8)+(4*7)+(3*3)+(2*6)+(1*1)=157
157 % 10 = 7
So 73873-61-7 is a valid CAS Registry Number.
73873-61-7Relevant articles and documents
Electrocatalytic hydrogenation of benzoic acids in a proton-exchange membrane reactor
Atobe, Mahito,Fukazawa, Atsushi,Shida, Naoki,Shimizu, Yugo
supporting information, p. 7363 - 7368 (2021/09/08)
The highly efficient chemoselective electrocatalytic hydrogenation of benzoic acids (BAs) to cyclohexanecarboxylic acids (CCAs) was carried out in a proton-exchange membrane reactor under mild conditions without hydrogenation of the carboxyl group. Among the investigated catalysts, the PtRu alloy catalyst was found to be the most suitable for achieving high current efficiencies for production of CCAs. An electrochemical spillover mechanism on the PtRu alloy catalyst was also proposed.
