740-57-8

Basic information

• Product Name: H-PHE-BETANA
• Synonyms: H-Phe-bNA;(2S)-2-amino-N-(2-naphthyl)-3-phenyl-propionamide;(2S)-2-amino-N-naphthalen-2-yl-3-phenylpropanamide;(2S)-2-azanyl-N-naphthalen-2-yl-3-phenyl-propanamide;H-Phe-βNA;N-2-naphthylphenylalaninamide;L-Phe-bNA;L-Phenylalanine b-naphthylamide≥ 99% (TLC)
• CAS NO: 740-57-8
• Molecular Formula: C₁₉H₁₈N₂O
• Molecular Weight: 290.36
• EINECS: 212-009-9
• Product Categories: Amino Acids;I - Z;Modified Amino Acids
• Mol File: 740-57-8.mol
• Article Data: 2

Chemical Properties

• Melting Point: 129-131 °C(lit.)
• Boiling Point: 550.4 °C at 760 mmHg
• Flash Point: 286.7 °C
• Appearance: /
• Density: 1.22 g/cm³
• Vapor Pressure: 3.66E-12mmHg at 25°C
• Refractive Index: 1.69
• Storage Temp.: −20°C
• PKA: 14.09±0.30(Predicted)
• CAS DataBase Reference: H-PHE-BETANA(CAS DataBase Reference)
• NIST Chemistry Reference: H-PHE-BETANA(740-57-8)
• EPA Substance Registry System: H-PHE-BETANA(740-57-8)

Safety Data

• Hazard Codes: Xn
• Statements: 20/21/22-40
• Safety Statements: 22-36
• WGK Germany: 3
• Hazardous Substances Data: 740-57-8(Hazardous Substances Data)

Usage

Description

H-PHE-BETANA, also known as L-phenylalanine amide, is an L-phenylalanine derivative obtained by formal condensation of the carboxy group of L-phenylalanine with the amino group of 2-naphthylamine. It is a white powder with unique chemical properties.

Uses

Used in Pharmaceutical Industry:
H-PHE-BETANA is used as a pharmaceutical intermediate for the synthesis of various drugs and medications. Its unique chemical structure allows it to be a key component in the development of new therapeutic agents.
Used in Research and Development:
H-PHE-BETANA is used as a research compound in the field of organic chemistry and biochemistry. Its unique properties make it a valuable tool for studying various chemical reactions and biological processes.
Used in Cosmetic Industry:
H-PHE-BETANA is used as an active ingredient in cosmetic products for its potential skin care benefits. Its unique chemical structure may contribute to improving skin health and appearance.
Used in Food Industry:
H-PHE-BETANA is used as a flavoring agent in the food industry. Its unique chemical properties may contribute to enhancing the taste and aroma of various food products.

InChI:InChI=1/C19H18N2O/c20-18(12-14-6-2-1-3-7-14)19(22)21-17-11-10-15-8-4-5-9-16(15)13-17/h1-11,13,18H,12,20H2,(H,21,22)/t18-/m0/s1

Upstream product

• 1161-13-3 N-Cbz-L-Phe 
• 13200-85-6 N-formyl-L-phenylalanine 
• 91-59-8 naphthalen-2-ylamine 
• 13734-34-4 N-tert-butoxycarbonyl-L-phenylalanine 
• 109057-27-4 tert-butyloxycarbonyl-L-phenylalanine 2-naphthylamide 
• 16876-73-6 N-Benzyloxycarbonyl-L-phenylalanin-<2>naphthylamid 
• 5249-47-8 N-Formyl-L-phenylalanin-<2>naphthylamid 

Relevant articles and documents

Addressing the stability of C-capped dipeptide efflux pump inhibitors that potentiate the activity of levofloxacin in Pseudomonas aeruginosa

Synthetic optimization of a biologically labile class of dipeptides that function as efflux pump inhibitors to potentiate the antibacterial agent levofloxacin in Pseudomonas aeruginosa has led to the discovery of a related series of compounds that are completely stable in a variety of biological matrices. Other than the stability profile, the in vitro profile of the new series is essentially identical to that observed with the original one. A prototypical compound from the new series demonstrates potentiation in an in vivo model of infection.