74050-54-7Relevant articles and documents
Synthesis of β-acetoxy alcohols by PhI(OAc)2-mediated metal-free diastereoselective β-acetoxylation of alcohols
Zhao, Chun-Yang,Li, Liang-Gui,Liu, Qing-Rong,Pan, Cheng-Xue,Su, Gui-Fa,Mo, Dong-Liang
, p. 6795 - 6803 (2016/07/23)
β-Acetoxy alcohols can be synthesized in good yields with excellent diastereoselectivity from tertiary alcohols through PhI(OAc)2-mediated metal-free β-acetoxylation. Mechanistic studies showed that the β-acetoxylation process might undergo dehydration and sequential highly regioselective and diastereoseletive dioxygenation. Gram scale and diverse useful scaffolds could be prepared via this β-acetoxylation process.