7409-30-5

Basic information

• Product Name: 4-nitrobenzylamine
• Synonyms: 4-Nitrobenzenemethanamine;18600-42-5 (Mono-hydrochloride);Benzenemethanamine, 4-nitro-;Para-nitrobenzylamine;(4-Nitrophenylmethyl)amine;(4-Nitrophenyl)MethanaMine;1-((4-Nitrophenyl)
• CAS NO: 7409-30-5
• Molecular Formula: C₇H₈N₂O₂
• Molecular Weight: 152.15
• Mol File: 7409-30-5.mol
• Article Data: 55

Chemical Properties

• Melting Point: 117-119℃
• Boiling Point: 298℃
• Flash Point: 134℃
• Appearance: /
• Density: 1.254
• Storage Temp.: 2-8°C(protect from light)
• PKA: 8.36±0.10(Predicted)
• CAS DataBase Reference: 4-nitrobenzylamine(CAS DataBase Reference)
• NIST Chemistry Reference: 4-nitrobenzylamine(7409-30-5)
• EPA Substance Registry System: 4-nitrobenzylamine(7409-30-5)

Safety Data

• Hazardous Substances Data: 7409-30-5(Hazardous Substances Data)

Usage

General Description

4-Nitrobenzylamine is an organic compound with the molecular formula C7H8N2O2. It is categorized as an aromatic amine containing a benzene ring and an attached nitro group, making it both an aminobenzene and a nitrobenzene. 4-nitrobenzylamine appears as a light yellow solid at room temperature. It has applications in numerous chemical reactions due to its reactivity and versatility, playing a crucial role in the pharmaceutical and chemical industries. Exposure to 4-nitrobenzylamine may cause irritation to the eyes and skin, and it should be handled with care in line with standard safety protocols.

Upstream product

• 100-97-0 hexamethylenetetramine 
• 100-14-1 4-nitrobenzyl chloride 
• 100-11-8 1-bromomethyl-4-nitro-benzene 
• 62133-07-7 2-(4-nitrobenzyl)-1H-isoindole-1,3(2H)-dione 
• 540-69-2 ammonium formate 
• 555-16-8 4-nitrobenzaldehdye 
• 1074-82-4 potassium phtalimide 
• 100-46-9 benzylamine 
• 33499-32-0 (E/Z)-4-nitrobenzaldehyde O-methyl oxime 
• 21081-63-0 2-(3-nitrobenzyl)isoindoline-1,3-dione 
• 82619-55-4 N-(p-nitrophenyl)-4,6-dimethylpyrimidinium bromide 
• 1129-37-9 4-nitrobenzaldehyde oxime 
• 3145-86-6 4-nitrobenzyl iodide 
• 7647-01-0 hydrogenchloride 

Downstream Products

• 93734-90-8 N,N′-bis(4-nitrobenzyl)urea 
• 104413-36-7 dichloro-acetic acid-(4-nitro-benzylamide) 
• 122704-02-3 1,6,7,1',6',7'-hexahydroxy-5,5'-diisopropyl-3,3'-dimethyl-[2,2']binaphthyl-8,8'-dicarbaldehyde bis-(4-nitro-benzylimine) 
• 101092-83-5 N,N'-bis-(4-nitro-benzyl)-thiourea 
• 111437-15-1 4-methyl-N-[(4-nitrophenyl)methyl]benzenesulfonamide 
• 4403-71-8 (4-aminomethyl)aniline 
• 137832-14-5 (E)-N-(4-nitrobenzyl)-1-(4-nitrophenyl)methanimine 
• 100872-24-0 benzylidene-(4-nitro-benzyl)-amine 
• 34907-24-9 N-(p-Nitrobenzyl) benzamide 
• 873990-16-0 methyl 4-nitrobenzylcarbamate 
• 38426-11-8 2-chloro-N-(4-nitrobenzyl)acetamide 
• 32121-03-2 N-(4-nitrobenzyl)benzenesulfonamide 
• 10269-00-8 N-(4-nitrobenzyl)-2,4-dinitroaniline 
• 92099-52-0 4-Chlor-butan-sulfonsaeure-(1)-<4-nitro-benzylamid> 

Relevant articles and documents

A novel three-component reaction toward dihydrooxazolopyridines

Isocyano dihydropyridones accessible via a recently reported multicomponent reaction react with aldehydes and amines to afford dihydrooxazolopyridines in high yield. The scope and limitations of this novel multicomponent reaction were investigated. The ef

Reaction of Diisobutylaluminum Borohydride, a Binary Hydride, with Selected Organic Compounds Containing Representative Functional Groups

The binary hydride, diisobutylaluminum borohydride [(iBu)2AlBH4], synthesized from diisobutylaluminum hydride (DIBAL) and borane dimethyl sulfide (BMS) has shown great potential in reducing a variety of organic functional groups. This unique binary hydride, (iBu)2AlBH4, is readily synthesized, versatile, and simple to use. Aldehydes, ketones, esters, and epoxides are reduced very fast to the corresponding alcohols in essentially quantitative yields. This binary hydride can reduce tertiary amides rapidly to the corresponding amines at 25 °C in an efficient manner. Furthermore, nitriles are converted into the corresponding amines in essentially quantitative yields. These reactions occur under ambient conditions and are completed in an hour or less. The reduction products are isolated through a simple acid-base extraction and without the use of column chromatography. Further investigation showed that (iBu)2AlBH4 has the potential to be a selective hydride donor as shown through a series of competitive reactions. Similarities and differences between (iBu)2AlBH4, DIBAL, and BMS are discussed.

Locking the Dynamic Axial Chirality of Biphenyl Crown Ethers through Threading

This paper describes the syntheses of [2]rotaxanes comprising 23- and 26-membered biphenyl crown ethers as the macrocyclic components and secondary ammonium ions as the dumbbell-shaped components, and the locking of the dynamic axial chirality of the biph