74129-15-0 Usage
Description
2-[(4-bromophenyl)methyl]pyridine is an organic compound that serves as a crucial intermediate in the synthesis of various pharmaceuticals. It is characterized by its unique molecular structure, which features a pyridine ring with a bromophenylmethyl group attached to the second position.
Uses
Used in Pharmaceutical Industry:
2-[(4-bromophenyl)methyl]pyridine is used as a key intermediate in the synthesis of Bromopheniramine Maleate, a derivative of Pheniramine (P297200). 2-[(4-bromophenyl)methyl]pyridine is utilized for the treatment of allergic conditions such as hay fever or urticaria, due to its effectiveness in alleviating symptoms associated with these conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 74129-15-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,4,1,2 and 9 respectively; the second part has 2 digits, 1 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 74129-15:
(7*7)+(6*4)+(5*1)+(4*2)+(3*9)+(2*1)+(1*5)=120
120 % 10 = 0
So 74129-15-0 is a valid CAS Registry Number.
InChI:InChI=1/C12H10BrN/c13-11-6-4-10(5-7-11)9-12-3-1-2-8-14-12/h1-8H,9H2
74129-15-0Relevant articles and documents
Direct Triflylation of Benzylic C—H Bonds with Pyridine as a Directing Group
Yang, Jun,Hu, Juanjuan,Huang, Yangen,Xu, Xiuhua,Qing, Fengling
supporting information, p. 867 - 870 (2017/06/27)
The first example of benzylic C—H triflylation was accomplished with pyridine as a directing group. The reaction of various 2-benzylpyridines and (CF3SO2)2O in the presence of NEt3 in CH2Cl2 proceeded smoothly to afford the corresponding benzyl triflones in moderate to high yields.
Rapid Mo(CO)6 catalysed one-pot deoxygenation of heterocyclic halo-benzyl alcohols with Lawesson's reagent
Wu, Xiongyu,Mahalingam,Alterman, Mathias
, p. 1501 - 1504 (2007/10/03)
A fast and efficient microwave promoted one-pot method for deoxygenation of heterocyclic halo-benzyl alcohols has been developed. The method does not cause dehalogenation of the substrates and provides the deoxygenated products in high yield after only 30 min.