741698-79-3

Basic information

• Product Name: Phenol, 4-bromo-2-(1-methylpropyl)-
• CAS NO: 741698-79-3
• Molecular Formula: C10H13BrO
• Molecular Weight: 229.117
• Mol File: 741698-79-3.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: Phenol, 4-bromo-2-(1-methylpropyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Phenol, 4-bromo-2-(1-methylpropyl)-(741698-79-3)
• EPA Substance Registry System: Phenol, 4-bromo-2-(1-methylpropyl)-(741698-79-3)

Safety Data

• Hazardous Substances Data: 741698-79-3(Hazardous Substances Data)

Upstream product

• 89-72-5 2-sec-butylphenol 

Downstream Products

• 1188335-80-9 ethyl 2-(2-sec-butyl-4-bromophenoxy)acetate 
• 1188335-76-3 2-sec-butyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol 

Relevant articles and documents

3,3′-Disubstituted bipolar biphenyls as inhibitors of nuclear receptor coactivator binding

A series of bipolar biphenyl compounds was synthesized as proteomimetic analogs of the LXXLL penta-peptide motif responsible for the binding of coactivator proteins to the nuclear hormone receptor coactivator binding domain. These compounds were subjected

MODULATORS OF NUCLEAR RECEPTOR CO-REGULATORY PROTEIN BINDING

Disclosed are novel compounds and compositions for inhibition of androgen and estrogen receptor signaling, methods for inhibiting androgen signaling, methods for inhibiting estrogen signaling, methods for inhibiting the interaction between a co-regulatory protein and an androgen or estrogen receptor, and methods for treating cancer.

AMINO ALCOHOL DERIVATIVE, MEDICINAL COMPOSITION CONTAINING THE SAME, AND USE OF THESE

The present invention provides compounds represented by general formula (I): a prodrug thereof, or pharmaceutical acceptable salts thereof, wherein R1 is hydrogen or lower alkyl; each of R2 and R3 is independently hydrogen or lower alkyl; each of R4, R5 and R6 is independently hydrogen, halogen, lower alkyl or lower alkoxy; R7 is hydrogen or lower alkyl; R8 is hydrogen, halogen, lower alkyl, lower alkoxy, etc; R9 is -COR10, -A1-COR10, -O-A2-COR10, etc; Ar is optionally substituted phenyl or heteroaryl; and A is a bond, -OCH2-, etc, which exhibit potent and selective β3-adrenoceptor stimulating activities. The present invention also provides pharmaceutical compositions containing said compound, and uses thereof.