7417-28-9 Usage
Description
2,4(1H,3H)-Pyrimidinedione, 5-hydroxy-6-methyl(9CI) is a chemical compound with the molecular formula C5H6N2O3. It is a derivative of pyrimidine and has a hydroxyl group and a methyl group attached to the pyrimidine ring. 2,4(1H,3H)-Pyrimidinedione, 5-hydroxy-6-methyl(9CI) is commonly used as a building block in organic synthesis and pharmaceutical research due to its potential biological activity and the antiviral, anticancer, and antioxidant properties of its derivatives.
Uses
Used in Pharmaceutical Research:
2,4(1H,3H)-Pyrimidinedione, 5-hydroxy-6-methyl(9CI) is used as a building block in pharmaceutical research for the development of new drugs. Its derivatives have been investigated for their potential therapeutic effects against various medical conditions, making it a valuable chemical in the field of medicinal chemistry and drug development.
Used in Organic Synthesis:
2,4(1H,3H)-Pyrimidinedione, 5-hydroxy-6-methyl(9CI) is used as a building block in organic synthesis for the creation of various chemical compounds. Its unique structure and functional groups make it a versatile component in the synthesis of complex organic molecules.
Used in Antiviral Applications:
Derivatives of 2,4(1H,3H)-Pyrimidinedione, 5-hydroxy-6-methyl(9CI) have been studied for their antiviral properties, making it a potential candidate for the development of antiviral drugs.
Used in Anticancer Applications:
Derivatives of 2,4(1H,3H)-Pyrimidinedione, 5-hydroxy-6-methyl(9CI) have been investigated for their anticancer properties, indicating its potential use in the development of cancer treatments.
Used in Antioxidant Applications:
Derivatives of 2,4(1H,3H)-Pyrimidinedione, 5-hydroxy-6-methyl(9CI) have been studied for their antioxidant properties, suggesting its potential use in the development of antioxidants for various applications.
Check Digit Verification of cas no
The CAS Registry Mumber 7417-28-9 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 7,4,1 and 7 respectively; the second part has 2 digits, 2 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 7417-28:
(6*7)+(5*4)+(4*1)+(3*7)+(2*2)+(1*8)=99
99 % 10 = 9
So 7417-28-9 is a valid CAS Registry Number.
InChI:InChI=1/C5H6N2O3/c1-2-3(8)4(9)7-5(10)6-2/h8H,1H3,(H2,6,7,9,10)
7417-28-9Relevant articles and documents
A new synthesis of 5-hydroxy-6-methyluracil
Grabovskiy, Stanislav A.,Murinov, Yuri I.,Kabal'nova, Natalia N.
, p. 6025 - 6028,4 (2020/08/20)
Dehydration of 5,6-dihydro-5,6-dihydroxy-6-methyl- and 5,6-dihydro-5,6- dihydroxy-1,3,6-trimethyl-uracil in 0.4 M aqueous sulfuric acid gives 5-hydroxy-6-methyl- and 5-hydroxy-1,3,6-trimethyluracil in quantitative yields. Two possible mechanisms have been examined using the mPW1k/6-311+G(2df,2pd)// mPW1k/6-31+G(d,p) method for the transformation of methylated and non-methylated 5,6-dihydro-5,6-dihydroxy-6-methyluracils into the corresponding 5-hydroxy-6-methyluracils. The first is a hydride C5-C6 shift occurring in concert with the loss of a water molecule and formation of the corresponding protonated 5,6-dihydro-5-oxo-6-methyluracils. The second is an acid-catalyzed dehydration reaction to yield 5-hydroxy-6-methyluracils. The calculations demonstrated that the second pathway was energetically most favorable.
SYNTHESIS OF BISURACIL SULFOLANE DERIVATIVES
Tolstikov, G. A.,Sharipova, F. V.,Baltina, L. A.,Spirikhin, L. V.
, p. 1030 - 1032 (2007/10/02)
Bisuracil sulfolane derivatives have been synthesized using the silyl method of nucleoside synthesis in the presence of SnCl4.The necessary starting materials were 5-hydroxy-6-methyluracil (prepared by oxidation of 6-methyluracil with ammonium persulfate in aqueous medium) and trans-3,4-diacetoxysulfolane (prepared from trans-3,4-dihydroxysulfolane).The structures of the bisuracil sulfolane derivatives were established based on their spectral data and elemental analysis.