742058-27-1

Basic information

• Product Name: 1H-Pyrazole-3-carboxylic acid, 5-[4-(phenylmethoxy)phenyl]-, methyl ester
• CAS NO: 742058-27-1
• Molecular Formula: C18H16N2O3
• Molecular Weight: 308.337
• Mol File: 742058-27-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1H-Pyrazole-3-carboxylic acid, 5-[4-(phenylmethoxy)phenyl]-, methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Pyrazole-3-carboxylic acid, 5-[4-(phenylmethoxy)phenyl]-, methyl ester(742058-27-1)
• EPA Substance Registry System: 1H-Pyrazole-3-carboxylic acid, 5-[4-(phenylmethoxy)phenyl]-, methyl ester(742058-27-1)

Safety Data

• Hazardous Substances Data: 742058-27-1(Hazardous Substances Data)

Upstream product

• 742058-26-0 sodium 3-(4-benzyloxyphenyl)-1-methoxycarbonyl-3-oxopropen-1-olate 
• 2644-70-4 hydrazine hydrochloride 

Relevant articles and documents

BIS(HETERO)ARYL CARBOXAMIDE DERIVATIVES FOR USE AS PGI2 ANTAGONISTS

The present invention relates to aryl or heteroaryl amido alkane derivatives of formula (I) wherein R6 represents carboxy or tetrazolyl, which are useful as an active ingredient of pharmaceutical preparations. The aryl or heteroaryl amido alkanes of the present invention have PGI2 antagonistic activity, and can be used for the prophylaxis and treatment of diseases associated with PGI2 activity.Such diseases include urological diseases or disorder as follows: bladder outlet obstruction, overactive bladder, urinary incontinence, detrusor hyper-reflexia, detrusor instability, reduced bladder capacity, frequency of micturition, urge incontinence, stress incontinence, bladder hyperreactivity, benighn prostatic hypertrophy (BPH), prostatitis, urinary frequency, nocturia, urinary urgency, pelvic hypersensitivity, urethritis, pelvic pain syndrome, prostatodynia, cystitis, or idiophatic bladder hypersensitivity.The compounds of the present invention are also useful for treatment of pain including, but not limited to inflammatory pain, neuropathic pain, acute pain, chronic pain, dental pain, premenstrual pain, visceral pain, headaches, and the like; hypotension;hemophilia and hemorrhage; and inflammation, since the diseases also relate to PGI2.