7424-54-6Relevant articles and documents
Preparation technology of 3,5-heptanedione
-
Paragraph 0019; 0020, (2018/04/21)
The invention discloses a preparation technology of 3,5-heptanedione. The technology comprises the steps of reacting ethyl propionate with methyl ethyl ketone in the presence of a water-insoluble aprotic solvent to obtain 3,5-heptanedione. According to the preparation technology of 3,5-heptanedione provided by the present invention, due to use of the water-insoluble aprotic solvent as a reaction solvent, the solvent is easy to recycle and production cost is saved.
Preparation method of medical intermediate beta-diketone compound
-
Paragraph 0023; 0024; 0025; 0026; 0027; 0028; 0029-0034, (2018/06/16)
The invention provides a preparation method of a medical intermediate beta-diketone compound. The preparation method comprises the step of performing a reaction on a ketone compound shown as a formulaI and an ester compound shown as a formula II in an organic solvent in the presence of an alkali catalyst to obtain the beta-diketone compound shown as a formula III, wherein the formula I is R1-CO-CHR2R3, the formula II is R4-CO-OR5 and the formula III is R1-CO-C(R2R3)-CO-R4. By the preparation method, the selectivity and the reaction yield of the product can be effectively increased, the reaction yield can reach 72.4%, the post-reaction treatment difficulty is reduced, the pollution to the environment is reduced, the production cost is reduced, and the economic efficiency and safety of production are improved.
Preparation method of beta-dione compound
-
Paragraph 0038-0039; 0041; 0043; 0045; 0047; 0049, (2017/11/29)
The invention relates to the field of compound preparation, and discloses a preparation method of a beta-dione compound. The method comprises: in the presence of a solvent and alkali metal potassium alcoholate, reacting methyl carboxylate with ketone. The method is high in yield, is safe, and is suitable for industrial application. Particularly, when 3,5-heptadione is prepared through the method, the yield of 3,5-heptadione can reach more than 60%, wherein the yield is far more higher than that in the prior art by taking DMF as a solvent.