744-46-7 Usage
Description
HIPPURYL-ARG, also known as Hippuryl-L-arginine, is a synthetic peptide compound commonly utilized as a substrate in various biochemical and enzymatic assays. It consists of a hippuric acid moiety linked to an L-arginine residue, which allows for the assessment of enzymatic activity, particularly of peptidases and proteases. HIPPURYL-ARG is widely recognized for its role in the detection and quantification of enzyme activity, making it a valuable tool in research and diagnostic applications.
Uses
Used in Enzyme Assays:
HIPPURYL-ARG is used as a substrate for the detection and quantification of various peptidases and proteases. It serves as a reliable and sensitive indicator of enzyme activity, allowing researchers to study the function and regulation of these enzymes in different biological systems.
Used in Pharmaceutical Research:
In the pharmaceutical industry, HIPPURYL-ARG is employed as a substrate for the identification and characterization of potential drug targets, particularly those related to proteolytic enzymes. By monitoring the activity of these enzymes using HIPPURYL-ARG, researchers can gain insights into their role in disease processes and develop targeted therapeutic strategies.
Used in Diagnostic Applications:
HIPPURYL-ARG is utilized in the development of diagnostic tests for various conditions, particularly those involving altered peptidase or protease activity. By measuring the rate of hydrolysis of HIPPURYL-ARG, clinicians can assess the presence and severity of specific enzymatic abnormalities, aiding in the diagnosis and monitoring of disease progression.
Used in Research on Aminopeptidase from Trogoderma granarium:
HIPPURYL-ARG is used as a substrate for studying the aminopeptidase enzyme derived from Trogoderma granarium, a storage pest that affects various commodities. Understanding the enzyme's activity and specificity can provide valuable information for the development of targeted pest control strategies.
Used in Research on Exopeptidase from Bactrocera oleae Gmelin, midgut of Plagiodera versicolora:
HIPPURYL-ARG serves as a substrate for investigating the exopeptidase enzyme found in the midgut of Bactrocera oleae Gmelin and Plagiodera versicolora, both of which are significant agricultural pests. This research can contribute to the development of novel pest management approaches by targeting the enzymes involved in their digestive processes.
Used in Research on Carboxypeptidase from Pichia pastoris:
HIPPURYL-ARG is employed as a substrate for examining the carboxypeptidase enzyme from Pichia pastoris, a yeast species with biotechnological applications. Studying the enzyme's activity and properties can lead to advancements in the production of recombinant proteins and other biotechnological processes.
Biochem/physiol Actions
Hippuryl-Arg is a synthetic substrate for carboxypeptidase B, and aminopeptidase. The enzyme carboxypeptidase acts on C terminal of arginine and lysine.
Check Digit Verification of cas no
The CAS Registry Mumber 744-46-7 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 7,4 and 4 respectively; the second part has 2 digits, 4 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 744-46:
(5*7)+(4*4)+(3*4)+(2*4)+(1*6)=77
77 % 10 = 7
So 744-46-7 is a valid CAS Registry Number.
InChI:InChI=1/C15H21N5O4/c16-15(17)18-8-4-7-11(14(23)24)20-12(21)9-19-13(22)10-5-2-1-3-6-10/h1-3,5-6,11H,4,7-9H2,(H,19,22)(H,20,21)(H,23,24)(H4,16,17,18)
