74420-15-8

Basic information

• Product Name: 3-Bromo-7-azaindole
• Synonyms: 3-BROMO-7-AZAINDOLE;3-BROMO-1H-PYRROLO[2,3-B]PYRIDINE;1H-PYRROLO[2,3-B]PYRIDINE, 3-BROMO-;3-Bromo-7-azaindole (3-bromo-1H-pyrrolo[2,3-b]pyridine）;3-broMo-1H-pyrrolo[2,3-b]pyridine 5-(trifluoroMethyl)-1H-iMidazole;3-BroMo-pyrrolo[2,3-b]pyridine;3-Bromo-7-azaindole 97%
• CAS NO: 74420-15-8
• Molecular Formula: C₇H₅BrN₂
• Molecular Weight: 197.03
• Product Categories: Heterocycles;Halides;CHIRAL CHEMICALS;Fused Ring Systems;Azaindole;Building Blocks;Indole Derivatives;Miscellaneous Reagents;Azaindoles
• Mol File: 74420-15-8.mol
• Article Data: 28

Chemical Properties

• Melting Point: 172-175
• Boiling Point: 336.4 °C at 760 mmHg
• Flash Point: 157.3 °C
• Appearance: White to brown/Powder
• Density: 1.77 g/cm³
• Storage Temp.: Inert atmosphere,Store in freezer, under -20°C
• Solubility: Dichloromethane, Ethyl Acetate
• PKA: 5.89±0.20(Predicted)
• CAS DataBase Reference: 3-Bromo-7-azaindole(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Bromo-7-azaindole(74420-15-8)
• EPA Substance Registry System: 3-Bromo-7-azaindole(74420-15-8)

Safety Data

• Hazard Codes: Xi,Xn
• Statements: 22-37/38-41
• Safety Statements: 26-36/37/39
• RIDADR: UN 2811
• WGK Germany: 3
• HazardClass: IRRITANT
• PackingGroup: Ⅲ
• Hazardous Substances Data: 74420-15-8(Hazardous Substances Data)

Usage

Description

3-Bromo-7-azaindole is a chemical compound characterized by its yellow solid appearance. It is a derivative of the azaindole family, which is a group of heterocyclic compounds with potential applications in various fields due to their unique chemical properties.

Uses

Used in Pharmaceutical Industry:
3-Bromo-7-azaindole is used as a reagent for the preparation of biologically active Azaindoles. These Azaindoles are known for their diverse range of pharmacological properties, making them valuable in the development of new drugs and therapeutic agents.
Used in Chemical Synthesis:
3-Bromo-7-azaindole serves as a useful starter in 7-azaindole chemistry, which is an important area of research in the field of organic chemistry. 3-Bromo-7-azaindole's unique structure allows for the synthesis of various complex molecules with potential applications in different industries.

Upstream product

• 271-63-6 7-Azaindole 
• 156270-06-3 7-azaindolyl-3-carboxylic acid 

Downstream Products

• 271-63-6 7-Azaindole 
• 90929-77-4 1-(2-hydroxyethyl)-7-azaindole 
• 90929-76-3 3-(2-hydroxyethyl)-7-azaindole 
• 74420-08-9 3-Bromo-1H-pyrrolo<2,3-b>pyridine 7-oxide 
• 918525-02-7 3-bromo-1-(triisopropylsilyl)-1H-pyrrolo[2,3-b]pyridine 
• 1093759-49-9 1-(triisopropylsilyl)-1H-pyrrolo[2,3-b]pyridine 
• 1097221-10-7 3-(4-chlorophenyl)-1-phenyl-1H-pyrrolo[2,3-b]pyridine 
• 942070-47-5 2-methyl-2-propanyl 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrolo[2,3-b]pyridine-1-carboxylate 

Relevant articles and documents

Decarboxylative Bromination of Heteroarenes: Initial Mechanistic Insights

After an initial report from our laboratory describing metal-free decarboxylative halogenation of various azaheteroarenes, we set out to investigate the possible mechanism by which this chemistry occurs. Evidence from this mechanistic investigation sugges

Aryl halide and synthesis method and application thereof

The invention discloses a synthesis method of aryl halides (including aryl bromide shown as a formula (2) and aryl iodide shown as a formula (3)). All the systems are carried out in an air atmosphere,visible light is utilized to excite a substrate or a photosensitizer to catalyze the reaction; and in a reaction solvent, when aromatic hydrocarbon shown in the formula (1) and sodium bromide serve as raw materials, aryl bromide shown in the formula (2) is obtained through a reaction under the auxiliary action of an additive (protonic acid); or when aromatic hydrocarbon shown in the formula (1) and sodium iodide are used as raw materials, under the auxiliary action of an additive (protonic acid), aryl iodide shown in the formula (3) is obtained through reaction. The synthesis method has the advantages of cheap and accessible raw materials, simple reaction operation and mild reaction conditions. The method is compatible with the arylamine which is liable to be oxidized. The invention provides a new method for the synthesis of aryl halides, realizes the amplification of basic chemicals aryl halides including aryl bromide shown in the formula (2) and aryl iodide shown in the formula (3),and has wide application prospect and practical value.

COMPOUNDS FOR USING IN IMAGING AND PARTICULARLY FOR THE DIAGNOSIS OF NEURODEGENERATIVE DISEASES

The invention relates to compounds of formula (II) for using in imaging and particularly for the diagnosis of neurodegenerative diseases