74483-51-5 Usage
Description
3,4-Dichloro-6-(trifluoromethyl)toluene is an organic compound characterized by the presence of two chlorine atoms at the 3rd and 4th positions and a trifluoromethyl group at the 6th position on a toluene molecule. This halogenated aromatic compound is known for its potential reactivity and stability, making it a versatile building block in various chemical syntheses.
Uses
Used in Organic Synthesis:
3,4-Dichloro-6-(trifluoromethyl)toluene is used as an organic synthesis intermediate for the preparation of a variety of complex organic molecules. Its unique structural features, including the presence of multiple chlorine and fluorine atoms, facilitate its involvement in numerous chemical reactions, such as nucleophilic substitutions, electrophilic aromatic substitutions, and cross-coupling reactions, enabling the synthesis of a wide range of target compounds.
Used in Pharmaceutical Industry:
In the pharmaceutical sector, 3,4-Dichloro-6-(trifluoromethyl)toluene serves as a key intermediate in the synthesis of various medicinal compounds. Its reactivity and structural attributes make it a valuable component in the development of new drugs, particularly those targeting specific biological pathways or receptors. 3,4-Dichloro-6-(trifluoromethyl)toluene's ability to be modified and functionalized allows for the creation of potential therapeutic agents with improved pharmacological properties.
Used in Laboratory Research and Development:
3,4-Dichloro-6-(trifluoromethyl)toluene is also utilized in laboratory research and development processes, where it can be employed to explore novel chemical reactions, investigate the effects of halogenation on molecular properties, and study the behavior of aromatic compounds under various conditions. Its use in research settings contributes to the advancement of chemical knowledge and the discovery of new applications in various fields.
Used in Chemical Production Processes:
Finally, 3,4-Dichloro-6-(trifluoromethyl)toluene plays a role in chemical production processes, where it may be scaled up for the manufacturing of commercial products. Its stability and reactivity make it suitable for industrial applications, and its presence in the final products can contribute to their performance characteristics, such as thermal stability, resistance to degradation, or specific chemical functionalities.
Synthesis
500 ml of hydrogen fluoride, 600 ml of carbon tetrachloride and 140 g of 3,4-dichlorotoluene are reacted at 110° to 115° C. and 18.5 to 19.5 bar pressure. 151 g of a stubstance containing, in addition to 79.1% by weight of 3,4-dichlorotoluene, 20.2% by weight of 2-methyl-4,5-dichloro-benzotrifluoride, are obtained, corresponding to 74% of the theoretical yield, relative to 3,4-dichlorotoluene converted.
Check Digit Verification of cas no
The CAS Registry Mumber 74483-51-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,4,4,8 and 3 respectively; the second part has 2 digits, 5 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 74483-51:
(7*7)+(6*4)+(5*4)+(4*8)+(3*3)+(2*5)+(1*1)=145
145 % 10 = 5
So 74483-51-5 is a valid CAS Registry Number.
InChI:InChI=1/C8H5Cl2F3/c1-4-2-6(9)7(10)3-5(4)8(11,12)13/h2-3H,1H3
74483-51-5Relevant articles and documents
Process for the preparation of aromatic trifluoromethyl compounds
-
, (2008/06/13)
A process for the preparation of an aromatic trifluoromethyl compound which comprises contacting an aromatic compound of the formula STR1 wherein R1 denotes hydrogen, alkyl, aryl, aralkyl, aryloxy, arylthio, polyhalogenoalkoxy or polyhalogenoalkylthio and the aromatic substituents R1 can in turn be substituted by halogen, alkyl, polyhalogenoalkyl, polyhalogenoalkoxy, polyhalogenoalkylthio, nitro, chlorocarbonyl or chlorosulfonyl, and R2, R3, R4 and R5 are independently hydrogen, halogen or alkyl and two adjacent radicals of the group R1 to R5 can conjointly form a three-membered to five-membered alkylene radical, with carbon tetrachloride and hydrogen fluoride at a temperature in the range of 50° C. to 140° C. Certain new aromatic trifluoromethyl compounds which can prepared by such a process are also disclosed.
