749206-47-1Relevant articles and documents
A practical synthesis of 2-arylamino-6-alkylaminopurines from 2,6-dichloropurine
Ciszewski, Lech,Waykole, Liladhar,Prashad, Mahavir,Repic, Oljan
, p. 799 - 802 (2006)
A practical synthesis of N-[4-(6-cyclobutylamino-9H-purin-2-ylamino)- phenyl]-N-methyl acetamide (QAB205, 5a), an anti-asthmatic agent, is described from 2,6-dichloropurine (1) by base-assisted substitution of the 6-chloro substituent with cyclobutylamine