749932-17-0

Basic information

• Product Name: 4-BROMO-1-DIFLUOROMETHYL-2-FLUOROBENZENE
• Synonyms: 4-BROMO-1-DIFLUOROMETHYL-2-FLUOROBENZENE;BENZENE, 4-BROMO-1-(DIFLUOROMETHYL)-2-FLUORO-;4-Bromo-1-(difluoromethyl)-2-fluorobenzene, 4-Bromo-alpha,alpha,2-trifluorotoluene;4-Bromo-2-fluorobenzal fluoride;1-Bromo-3-fluoro-4-difluoromethylbenzene
• CAS NO: 749932-17-0
• Molecular Formula: C₇H₄BrF₃
• Molecular Weight: 225.01
• Product Categories: Aryl;Building Blocks;C7;Chemical Synthesis;Difluoromethyl;Fluorinated Building Blocks;Halogenated Hydrocarbons;Organic Building Blocks;Organic Fluorinated Building Blocks;Fluorine series
• Mol File: 749932-17-0.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 199℃
• Flash Point: 76°C
• Appearance: /
• Density: 1.676g/mLat 25℃
• Vapor Pressure: 0.491mmHg at 25°C
• Refractive Index: n20/D 1.495
• CAS DataBase Reference: 4-BROMO-1-DIFLUOROMETHYL-2-FLUOROBENZENE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-BROMO-1-DIFLUOROMETHYL-2-FLUOROBENZENE(749932-17-0)
• EPA Substance Registry System: 4-BROMO-1-DIFLUOROMETHYL-2-FLUOROBENZENE(749932-17-0)

Safety Data

• Hazard Codes: Xn
• Statements: 20/21/22-36/37/38
• Safety Statements: 26-36/37
• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 749932-17-0(Hazardous Substances Data)

Usage

General Description

4-Bromo-1-difluoromethyl-2-fluorobenzene is a chemical compound that belongs to the class of difluoromethylbenzene derivatives. It is a halogenated aromatic compound with the molecular formula C7H4BrF3. This chemical is commonly used as an intermediate in the synthesis of various pharmaceuticals, agrochemicals, and other fine chemicals. It exhibits a high level of reactivity and is often used as a building block in the production of more complex organic compounds. Additionally, 4-Bromo-1-difluoromethyl-2-fluorobenzene is used as a reagent in organic synthesis and as a reference standard in analytical chemistry. It is important to handle this chemical with caution due to its potential health hazards and environmental impact.

InChI:InChI=1/C7H4BrF3/c8-4-1-2-5(7(10)11)6(9)3-4/h1-3,7H

Upstream product

• 57848-46-1 4-bromo-2-fluorobenzaldehyde 

Downstream Products

• 445303-65-1 2-[3-(difluoromethyl)-4-fluoro-phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 
• 1354286-94-4 N-(5-(4-(difluoromethyl)-3-fluorophenyl)-2-morpholinopyridin-4-yl)-5,7-difluoro-3-methyl-2-(pyridin-2-yl)quinolin-4-amine 
• 1310949-75-7 2-(4-(difluoromethyl)-3-fluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 
• 749932-18-1 1-cyclopentyl-3-[4-(difluoromethyl)-3-fluorophenyl]propan-1-one 

Relevant articles and documents

HYDROXY ISOXAZOLE COMPOUNDS USEFUL AS GPR120 AGONISTS

The present invention relates to a compound represented by formula (I) : and pharmaceutically acceptable salts thereof are disclosed as useful for treating or preventing diabetes, hyperlipidemia, obesity, NASH, inflammation related disorders, and related diseases and conditions. The compounds are useful as agonists of the G-protein coupled receptor GPR120. Pharmaceutical compositions and methods of treatment are also included.

INHIBITORS OF HEPATITIS C VIRUS RNA-DEPENDENT RNA POLYMERASE, AND COMPOSITIONS AND TREATMENTS USING THE SAME

The invention relates to compounds of the formula (I) and to pharmaceutically acceptable salts, solvates, prodrugs and metabolites thereof, wherein W, Z, R1and R2, are as defined herein. The invention also relates to methods of treating Hepatitis C virus in mammals by administering the compounds of formula (I), and to pharmaceutical compositions for treating such disorders, which contain the compounds of formula (I). The invention also relates to methods of preparing the compounds of formula (I).