7565-19-7

Basic information

• Product Name: N-BENZYL-N-METHYLGUANIDINE
• Synonyms: 1-benzyl-1-methylguanidine;N-benzyl-N-methylguanidine(SALTDATA: 0.5H2SO4);N-benzyl-N-methylguanidine 0.5H2SO4;Guanidine, N-Methyl-N-(phenylMethyl)-;N-Benzyl-N-methylguanidine hydroiodide
• CAS NO: 7565-19-7
• Molecular Formula: C₉H₁₃N₃
• Molecular Weight: 163.22
• Mol File: 7565-19-7.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 270.1°C at 760 mmHg
• Flash Point: 117.1°C
• Appearance: /
• Density: 1.07g/cm³
• Vapor Pressure: 0.00699mmHg at 25°C
• Refractive Index: 1.557
• Storage Temp.: 2-8°C
• CAS DataBase Reference: N-BENZYL-N-METHYLGUANIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: N-BENZYL-N-METHYLGUANIDINE(7565-19-7)
• EPA Substance Registry System: N-BENZYL-N-METHYLGUANIDINE(7565-19-7)

Safety Data

• Hazardous Substances Data: 7565-19-7(Hazardous Substances Data)

Usage

General Description

N-Benzyl-N-methylguanidine is a chemical compound that belongs to the class of organic compounds known as N-methylguanidines. It is an organonitrogen compound, also known as a carbamimidamido compound. This chemical is not naturally occurring and is often used in various fields of chemistry, such as in the production of polymers, foams, resins, and adhesives. It may also serve as a reagent in chemical synthesis. As with many chemical compounds, safe handling and storage are critical due to potential hazards and reactivity. Specific details about its properties, including molecular weight, boiling and melting points, and more, can be obtained through chemical databases.

InChI:InChI=1/C9H13N3/c1-12(9(10)11)7-8-5-3-2-4-6-8/h2-6H,7H2,1H3,(H3,10,11)

Upstream product

• 17356-08-0 thiourea 
• 103-67-3 benzyl-methyl-amine 
• 420-04-2 CYANAMID 
• 13426-94-3 N-methylbenzylamine hydrochloride 
• 2986-19-8 carbamimidothioic acid methyl ester 

Relevant articles and documents

Amidination of amines under microwave conditions using recyclable polymer-bound 1H-pyrazole-1-carboxamidine

A convenient one-step transformation of primary and secondary amines into the corresponding unprotected guanidines using 4-benzyl-3,5-dimethyl-1H- pyrazole-1-carboxamidine and its polymer-bound variant is described. The scopes and limitations of the method, the microwave-assistance of amidination as well as a recycling protocol are examined. Georg Thieme Verlag Stuttgart.

Novel linker for the solid-phase synthesis of guanidines

A novel linker for the generation of alkyl-, acyl- and arylguanidines as an attachment point in solid phase synthesis has been developed. Introduction of a suitably functionalized thiourea to Wang resin via a carbamate linkage, followed by displacement of sulfur with a 1°or 2°amine affords resin bound guanidines suitably protected for further manipulation. Activation of the thiourea with Mukaiyama's reagent allows for the generation of arylguanidines. Mild acid treatment effects deprotection and liberation from the resin to afford guanidines in good yield and high purity.