7575-93-1

Basic information

• Product Name: METHYL-D3 P-TOLUENESULFONATE
• Synonyms: METHYL-D3 P-TOLUENESULFONATE;(methyl-d3) 4-methylbenzenesulfonate
• CAS NO: 7575-93-1
• Molecular Formula: C₈H₁₀O₃S
• Molecular Weight: 189.25
• EINECS: 604-604-1
• Mol File: 7575-93-1.mol
• Article Data: 28

Chemical Properties

• Boiling Point: 82-84 °C(Press: 0.001 Torr)
• Appearance: /
• CAS DataBase Reference: METHYL-D3 P-TOLUENESULFONATE(CAS DataBase Reference)
• NIST Chemistry Reference: METHYL-D3 P-TOLUENESULFONATE(7575-93-1)
• EPA Substance Registry System: METHYL-D3 P-TOLUENESULFONATE(7575-93-1)

Safety Data

• Hazardous Substances Data: 7575-93-1(Hazardous Substances Data)

Usage

General Description

Methyl-D3 p-toluenesulfonate, also known as Methyl-D3 4-methylbenzenesulfonate, or Methyl-D3 tosylate, is a specialized chemical often used in organic synthesis and pharmaceutical research. It is a type of deuterated compound, meaning it contains deuterium ('D'), a heavy hydrogen isotope. Its molecular formula is C8H5D3O3S, reflecting the three deuterium atoms (D3) in its structure. Methyl-D3 p-toluenesulfonate is recognized for its relevance in creating compounds with improved properties, such as increased stability or metabolic tracking capabilities in pharmaceuticals. It is important to handle this compound with care due to potential safety hazards.

Upstream product

• 1849-29-2 1,1,1-trideuteromethanol 
• 98-59-9 p-toluenesulfonyl chloride 
• 811-98-3 d⁽⁴⁾-methanol 
• 84989-67-3 methyl 9,9-bis(ethylthio)fluorene-1-carboxylate 

Downstream Products

• 558-21-4 fluoromethane-d3 
• 51657-88-6 4-methoxy-N-(²H₃)methylaniline 
• 1026091-71-3 5-(N-benzoyl-N-([2H₃]methyl)amino)-1,4-dimethyltetrazolium tosylate 
• 1026091-76-8 C₄H₆⁽²⁾H₃N₅*C₇H₈O₃S 
• 1101136-15-5 ([4-²H₃]-2-butyn-1-yloxy)tert-butyldiphenylsilane 
• 1286216-69-0 benzyl 2-(methyl-d3)-3-oxobutanoate 
• 1407505-98-9 N-methyl-d₃ tert-butyl para-toluenesulfonylcarbamate 
• 94367-56-3 4-methyl-d3-biphenyl 
• 865-50-9 iodomethane-d3 
• 114379-92-9 1-(4-(methyl-d3)phenyl)ethan-1-one 
• 40419-72-5 o-methylbenzophenone-CD₃ 

Relevant articles and documents

Deuterated compound and application thereof in treatment of cancer

The present invention relates to a deuterated compound and application thereof in the treatment of cancer. Specifically, the present invention provides the compound of formula (I) and pharmaceuticallyacceptable salt or ester thereof, and a pharmaceutical composition thereof. The compound and the pharmaceutical composition are used for inhibiting or regulating the activity of tyrosine kinase and treating disease symptoms or symptoms including cancer mediated by tyrosine kinase.

Deuterated substituted butenamide and preparation method and application thereof

The invention belongs to the field of medicines, and particularly relates to deuterated substituted butenamide and a preparation method and application thereof. The deuterated substituted butenamide is prepared from the intermediate compound shown V. Compared with the prior art, the deuterated substituted butenamide is used. The deuterated substituted butane acetamide - N - oxide has a good anti-cancer effect, and the application prospect of the medicine is increased for anti-cancer treatment drugs. , The deuterated substituted butanamide and the deuterated substituted butane acetamide - N - oxide are prepared by the process, the operation is simple, the purity is high, the three wastes are few, and the process is environment-friendly and friendly.

Construction of Biaryls from Aryl Sulfoxides and Anilines by Means of a Sigmatropic Rearrangement

An unprecedented S?N variant of the benzidine rearrangement for construction of biaryls has been developed. Aryl sulfoxides underwent dehydrogenative coupling with anilines by successive treatment with trifluoromethanesulfonic anhydride and trifluorometha