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7576-65-0

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7576-65-0 Usage

Description

Solvent Yellow 114, also known as 2-(3-Hydroxyquinolin-2-yl)-1H-indene-1,3(2H)-dione, is a synthetic organic compound that has been historically used as a dye. However, it has been identified as a carcinogenic substance, leading to its ban in various applications, particularly in the food industry.

Uses

Used in Environmental Testing:
Solvent Yellow 114 is utilized in high-throughput screening approaches to inhibit anthrax lethal factor and in quantitative structure-activity relationship (QSAR) methods for anthrax treatment. This application aids in the development of effective countermeasures against anthrax threats.
Used in Dyes and Metabolites Research:
Although its use in the food industry has been banned, Solvent Yellow 114 may still be relevant in the study of dyes and their metabolites for research purposes, contributing to a better understanding of the chemical properties and potential risks associated with similar compounds.

Check Digit Verification of cas no

The CAS Registry Mumber 7576-65-0 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 7,5,7 and 6 respectively; the second part has 2 digits, 6 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 7576-65:
(6*7)+(5*5)+(4*7)+(3*6)+(2*6)+(1*5)=130
130 % 10 = 0
So 7576-65-0 is a valid CAS Registry Number.
InChI:InChI=1/C18H11NO3/c20-14-9-10-5-1-4-8-13(10)19-16(14)15-17(21)11-6-2-3-7-12(11)18(15)22/h1-9,15,20H

7576-65-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name 3-Hydroxy-2-(1,3-indandione-2-yl)quinoline

1.2 Other means of identification

Product number -
Other names Oil Yellow 114

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:7576-65-0 SDS

7576-65-0Synthetic route

3-hydroxy-quinaldine
613-19-4

3-hydroxy-quinaldine

phthalic anhydride
85-44-9

phthalic anhydride

2-(3-hydroxy-2-quinolinyl)-1H-indene-1,3(2H)-dione
7576-65-0

2-(3-hydroxy-2-quinolinyl)-1H-indene-1,3(2H)-dione

Conditions
ConditionsYield
at 250℃;
With zinc(II) chloride at 180℃;
at 200℃;
at 180℃; for 2h; Temperature;
phthalic anhydride
85-44-9

phthalic anhydride

3-ethoxy-2-methyl-quinoline-4-carboxylic acid
811432-11-8

3-ethoxy-2-methyl-quinoline-4-carboxylic acid

2-(3-hydroxy-2-quinolinyl)-1H-indene-1,3(2H)-dione
7576-65-0

2-(3-hydroxy-2-quinolinyl)-1H-indene-1,3(2H)-dione

Conditions
ConditionsYield
at 200℃;
phthalic anhydride
85-44-9

phthalic anhydride

3-hydroxy-2-methyl-4-quinolinecarboxylic acid
117-57-7

3-hydroxy-2-methyl-4-quinolinecarboxylic acid

2-(3-hydroxy-2-quinolinyl)-1H-indene-1,3(2H)-dione
7576-65-0

2-(3-hydroxy-2-quinolinyl)-1H-indene-1,3(2H)-dione

Conditions
ConditionsYield
at 240 - 245℃;
3-ethoxy-2-methyl-quinoline
57839-52-8

3-ethoxy-2-methyl-quinoline

2-(3-hydroxy-2-quinolinyl)-1H-indene-1,3(2H)-dione
7576-65-0

2-(3-hydroxy-2-quinolinyl)-1H-indene-1,3(2H)-dione

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: red phosphorus; water; hydriodic acid / auf Siedetemperatur
2: 200 °C
View Scheme
3-ethoxy-2-methyl-quinoline-4-carboxylic acid
811432-11-8

3-ethoxy-2-methyl-quinoline-4-carboxylic acid

2-(3-hydroxy-2-quinolinyl)-1H-indene-1,3(2H)-dione
7576-65-0

2-(3-hydroxy-2-quinolinyl)-1H-indene-1,3(2H)-dione

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 250 °C
2: red phosphorus; water; hydriodic acid / auf Siedetemperatur
3: 200 °C
View Scheme
indole-2,3-dione
91-56-5

indole-2,3-dione

2-(3-hydroxy-2-quinolinyl)-1H-indene-1,3(2H)-dione
7576-65-0

2-(3-hydroxy-2-quinolinyl)-1H-indene-1,3(2H)-dione

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: aqueous KOH
2: 250 °C
3: red phosphorus; water; hydriodic acid / auf Siedetemperatur
4: 200 °C
View Scheme
Multi-step reaction with 2 steps
1: aqueous KOH
2: 200 °C
View Scheme
2-(3-hydroxy-2-quinolinyl)-1H-indene-1,3(2H)-dione
7576-65-0

2-(3-hydroxy-2-quinolinyl)-1H-indene-1,3(2H)-dione

2-(4-bromo-3-hydroxy-2-quinolinyl)indan-1,3-dione
10319-14-9

2-(4-bromo-3-hydroxy-2-quinolinyl)indan-1,3-dione

Conditions
ConditionsYield
With 1,3-dibromo-5,5-dimethylimidazolidine-2,4-dione In dichloromethane at 40℃; for 8h; Time;97.5%
With bromine In sulfolane at 50 - 75℃; for 2h; Temperature;26.84 g
2-(3-hydroxy-2-quinolinyl)-1H-indene-1,3(2H)-dione
7576-65-0

2-(3-hydroxy-2-quinolinyl)-1H-indene-1,3(2H)-dione

bromine
7726-95-6

bromine

acetic acid
64-19-7

acetic acid

monobromo derivative

monobromo derivative

7576-65-0Relevant articles and documents

A quinophthalone compound, preparation method thereof and as the application of the light-absorbing material (by machine translation)

-

Paragraph 0025; 0026; 0027; 0028; 0032; 0036; 0040; 0044, (2018/10/01)

As shown in the formula A quinophthalone compound, preparation method thereof and as the application of the light-absorbing material. The preparation method comprises: the phthalic anhydride and 2 - methyl - 3 - hydroxy quinoline according to the weight 1: (3 - 5) is added to the reaction vessel, the solvent is 1, 3, 5 - trichlorobenzene, slow heating to 150 - 200 °C, and maintain at the temperature for 2 - 3 hours to carry out the condensation reaction. The application is shown in formula A quinophthalone compounds, core-shell structure nanometer titanium dioxide and the ultraviolet absorbent dispersed in the optical resin formed in the blue-light-resin material. Material has different band blue light to distinguish absorption performance, in that, the short wave harmful blue light to maintain low transmission, long wave band useful blue light and other band visible light to maintain high transmittance, is favorable to protect eyesight, better the ultraviolet light and blue light to the human eye's damage. (by machine translation)

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