76143-12-9Relevant articles and documents
Step-economical synthesis of tetrahydroquinolines by asymmetric relay catalytic Friedlaender condensation/transfer hydrogenation
Ren, Lei,Lei, Tao,Ye, Jia-Xi,Gong, Liu-Zhu
supporting information; experimental part, p. 771 - 774 (2012/02/05)
Two steps in one reaction: The title relay reaction relies on a combination of an achiral Lewis acid and a chiral Bronsted acid (B-H in the scheme). This one-pot method provides access to tetrahydroquinoline derivatives with multiple continuous stereogeni
1,3-dihydro-2H-imidazo[4,5-b]quinolin-2-ones - Inhibitors of blood platelet cAMP phosphodiesterase and induced aggregation
Meanwell,Roth,Smith,Wedding,Wright,Fleming,Gillespie
, p. 2906 - 2916 (2007/10/02)
A series of 1,3-dihydro-2H-imidazo[4,5-b]quinolin-2-one derivatives was synthesized and evaluated as inhibitors of cAMP hydrolysis by a crude human platelet phosphodiesterase preparation and as inhibitors of ADP- and collagen-induced aggregation of rabbit